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Gluteal Hidradenitis Suppurativa: Analysis of 83 Patients
N Riera-Martí1, E Vilarrasa2, C López-Llunell2
1Department of Dermatology, Hospital Universitari Parc Taulí, Sabadell (Barcelona), Spain.
Background:
In 2013, Canoui-Poitrine et al. identified three hidradenitis suppurativa (HS) phenotypes by a latent class (LC) analysis, based on anatomical sites of involvement.
Objective:
To improve the classification of the gluteal phenotype (LC3) patients given their diverse lesion types and differences in clinical profile.
Material And Methods:
We designed a bicentric study gathering all LC3 patients (n=83) from two hospitals. We conducted a two-step cluster analysis among them and also compared their characteristics with the rest of the HS patients (n=661).
Results:
Compared with global HS series, LC3 patients were more frequently non-obese men, with smoking habit, an associated arthropathy, and a more frequent history of pilonidal sinus. The analysis of LC3 patients yielded two clusters: cluster 1 (38.3%) included elderly female patients, with later diagnosis of the disease and more sinus tracts; cluster 2 (61.7%) encompassed more men with earlier disease onset and more nodules and folliculitis lesions.
Limitations:
The study's limitations include its retrospective nature, bicentric design, and small sample size.
Conclusion:
The heterogeneous clinical presentation of HS makes it essential to have a good classification of the patients. Gluteal phenotype could actually be classified into two "subphenotypes" with a different clinical profiles and management.
