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Related Concept Videos

Drugs for Treatment of Constipation-Predominant IBS01:21

Drugs for Treatment of Constipation-Predominant IBS

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Pharmacological therapies for IBS-C are designed to alleviate abdominal discomfort and enhance bowel function. In patients with IBS-C, fiber supplements may help soften stools and decrease straining, but may also lead to increased gas production and bloating. Osmotic laxatives like milk of magnesia are frequently used to soften stools and increase stool frequency in IBS-C patients. In addition, two drugs approved for use in severe IBS-C adult cases are linaclotide (Linzess) and lubiprostone...
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Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation01:30

Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation

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Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation
Irritable Bowel Syndrome (IBS) is classified into subtypes based on the predominant bowel habits as determined by the Bristol Stool Form Scale (BSFS). The subtypes are:
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Assessment of the Rectum and Anus01:25

Assessment of the Rectum and Anus

250
Evaluating the rectum and anus plays a crucial role in conducting a thorough physical examination of the gastrointestinal system. Although it may be uncomfortable and often embarrassing for the patient, it holds immense diagnostic value, particularly in detecting gastrointestinal diseases and abnormalities. This guide will explain how to perform this assessment using inspection and palpation methods.
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
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Irritable Bowel Syndrome III: Medical and Nursing Management01:30

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Managing Irritable Bowel Syndrome (IBS) involves a multifaceted approach, including lifestyle modifications, dietary changes, and medication.
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Drugs for Treatment of Diarrhea-Predominant IBS01:17

Drugs for Treatment of Diarrhea-Predominant IBS

192
Diarrhea-predominant irritable bowel syndrome (IBS-D) is a subtype of IBS characterized primarily by frequent, loose, or watery stools, abdominal pain, and abdominal discomfort. Therapeutic approaches to managing IBS-D include dietary changes, stress management techniques, and pharmaceutical interventions.
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...
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Drugs Affecting GI Tract Motility: Other Laxatives01:20

Drugs Affecting GI Tract Motility: Other Laxatives

248
Laxatives are primarily used to alleviate constipation, a common gastrointestinal disorder characterized by infrequent bowel movements and difficulty passing stools. They work by various mechanisms to increase the volume or frequency of bowel movements. The primary modes of action of laxatives include increasing stool bulk, softening the stool, stimulating intestinal motility, and osmotically drawing water into the intestines.
Osmotic or saline laxatives, like magnesium hydroxide or milk of...
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Electroacupuncture Combined with Chinese Medicine Ironing Therapy for Functional Constipation
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Perceptions, Definitions, and Therapeutic Interventions for Occasional Constipation: A Rome Working Group Consensus

Darren M Brenner1, Maura Corsetti2, Douglas Drossman3

  • 1Northwestern University Feinberg School of Medicine, Chicago, Illinois.

Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association
|October 5, 2023
PubMed
Summary
This summary is machine-generated.

Occasional constipation, a distinct condition from chronic constipation, is defined by infrequent, bothersome symptoms. First-line treatments include polyethylene glycol and stimulant laxatives, with magnesium compounds as a second option.

Keywords:
ConstipationFiberFunctional ConstipationLaxativesOccasional Constipation

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Area of Science:

  • Gastroenterology
  • Disorders of Gut-Brain Interaction

Background:

  • Functional constipation, a common disorder of gut-brain interaction, affects 12% globally.
  • Occasional constipation is a newly classified entity characterized by shorter, repetitive bouts of constipation.
  • This document provides a working definition and treatment algorithm for occasional constipation based on current research.

Approach:

  • A comprehensive review of the scientific literature on occasional constipation was conducted.
  • Rome IV criteria were used to establish a framework for the definition.
  • The Delphi method ensured 100% author agreement on recommendations.

Key Points:

  • Occasional constipation is defined as bothersome, infrequent functional constipation symptoms without alarm signs.
  • Polyethylene glycol and stimulant laxatives are recommended first-line treatments.
  • Magnesium-containing compounds are suggested for treatment-resistant cases.

Conclusions:

  • Occasional constipation is a distinct clinical entity requiring standardized definition and treatment.
  • Current recommendations provide a framework for future research into epidemiological and symptom-based outcomes.
  • Further studies are necessary to validate and refine treatment guidelines.