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Updated: Jul 14, 2025

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus
Published on: May 16, 2025
Erythematous plaques on the bilateral dorsal hands
Mohammad Fardos1, Benjamin R Cooper2, Sara Holt1
1HCA Healthcare/USF Morsani College of Medicine GME Programs Largo Medical Center Largo Florida USA.
This case study describes neutrophilic dermatosis of the dorsal hands, a rare condition causing painful, hemorrhagic, and pustular hand lesions. Early diagnosis and understanding this inflammatory process are key for effective patient management.
Area of Science:
- Dermatology
- Pathology
Background:
- Neutrophilic dermatosis of the dorsal hands is a rare cutaneous disorder.
- Characterized by sudden onset of painful, hemorrhagic, pustular bullae with violaceous rims on dorsal hands.
Observation:
- A 61-year-old male presented with a 1-week history of tender, hemorrhagic, and pustular bullae on both dorsal hands.
- Lesions evolved into ulcerative plaques with hemorrhagic crusting over 5 days.
Findings:
- Punch biopsy revealed diffuse dermal infiltrate of neutrophils, lymphocytes, and histiocytes.
- Epidermal changes included spongiosis and neutrophilic exocytosis.
- Leukocytoclastic vasculitis was notably absent.
Implications:
- Highlights the clinical and histopathological features of this rare inflammatory condition.
- Emphasizes the importance of accurate diagnosis for appropriate management of dorsal hand neutrophilic dermatosis.
- Contributes to the understanding of rare neutrophilic dermatoses.
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