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Related Experiment Video

Updated: Jul 14, 2025

Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy oSLO and Optical Coherence Tomography OCT
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Automated robot-assisted wide-field optical coherence tomography using structured light camera.

Xiaochen Li1, Yong Huang1, Qun Hao1

  • 1School of Optics and Photonics, Beijing Institute of Technology, No.5 South Zhongguancun Street, Haidian, Beijing, 100081, China.

Biomedical Optics Express
|October 6, 2023
PubMed
Summary
This summary is machine-generated.

This study introduces an automated system using a robotic arm and structured light camera to overcome the limited field of view in optical coherence tomography (OCT). The system enables large-area 3D OCT imaging for diverse applications.

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Area of Science:

  • Biomedical Imaging
  • Robotics
  • Optical Engineering

Background:

  • Conventional optical coherence tomography (OCT) systems have a limited field of view (FOV), restricting their application scope.
  • There is a need for advanced imaging techniques capable of high-resolution, large-area 3D reconstructions.

Purpose of the Study:

  • To develop and validate an automated system for large-area OCT scanning.
  • To enhance the applicability of OCT in biomedical and material inspection by overcoming FOV limitations.

Main Methods:

  • Integration of a robotic arm, a 3D structured light camera, and a portable OCT probe.
  • Utilizing the structured light camera to generate 3D point clouds for automated scan path planning.
  • Mounting the OCT probe on the robotic arm for precise sample scanning along predetermined paths.

Main Results:

  • The robotic arm achieved accurate positioning with an average absolute error of approximately 0.16 mm.
  • The system successfully generated high-resolution, large-area 3D OCT reconstructions.
  • Demonstrated imaging of ex vivo kidney, skin, and leaf blade samples over areas exceeding 20 cm2.

Conclusions:

  • The proposed automated system effectively overcomes FOV limitations in OCT.
  • The system enables accurate and efficient large-area 3D OCT imaging.
  • This technology holds significant potential for biomedical, industrial, and agricultural applications.