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Updated: Jun 20, 2026

A High-throughput Platform for the Screening of Salmonella spp./Shigella spp.
Published on: November 7, 2018
An integrated nationwide genomics study reveals transmission modes of typhoid fever in China
Ye Feng1,2, Hang Pan3, Beiwen Zheng4
1Sir Run Run Shaw Hospital, Zhejiang University School of Medicine , Hangzhou, China.
Importance:
Typhoid fever is a life-threatening disease caused by Salmonella enterica serovar Typhi, resulting in a significant disease burden across developing countries. Historically, China was very much close to the global epicenter of typhoid, but the role of typhoid transmission within China and among epicenter remains overlooked in previous investigations. By using newly produced genomics on a national scale, we clarify the complex local and global transmission history of such a notorious disease agent in China spanning the most recent five decades, which largely undermines the global public health network.
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