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Updated: Jul 14, 2025

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Discordant Uptake of Leg Thrombi Versus Pulmonary Emboli on 68 Ga-FAPI-46 PET/CT

Sang-Geon Cho1, Chan Park2, Jahae Kim1

  • 1From the Departments of Nuclear Medicine.

Clinical Nuclear Medicine
|October 6, 2023
PubMed

Insights

Fibroblast activation protein inhibitor (FAPI) PET imaging revealed differing uptake in venous thrombi versus pulmonary emboli in a single patient. This suggests variations in thrombus composition and age, even within the same individual.

Area of Science:

  • Nuclear Medicine
  • Radiochemistry
  • Vascular Biology

Background:

  • Fibroblast activation protein inhibitor (FAPI) Positron Emission Tomography (PET) is emerging as a key imaging modality for activated fibroblasts.
  • Activated fibroblasts play crucial roles in various pathological conditions, including thrombosis.

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