Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

A new method for intraoral patch testing.

T Axéll, E Spiechowicz, P O Glantz

    Contact Dermatitis
    |August 1, 1986
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Long-term clinical outcome in patients with glutathione synthetase deficiency.

    The Journal of pediatrics·2001
    Same author

    The pressure at the lower inflexion point has no relation to airway collapse in surfactant-treated premature lambs.

    Acta anaesthesiologica Scandinavica·2001
    Same author

    Angiogenic factors: vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (b-FGF) are not necessarily elevated in patients with advanced renal cell carcinoma.

    Anticancer research·2001
    Same author

    Is it necessary to order aspartate aminotransferase with alanine aminotransferase in clinical practice?

    Clinical chemistry·2001
    Same author

    Angiogenesis and angiogenic growth factors in Wilms tumor.

    The Journal of urology·2001
    Same author

    An open and flexible framework for computer aided surgical training.

    Studies in health technology and informatics·2001

    Intraoral patch testing revealed nickel sensitivity in two subjects. Despite minimal clinical signs, biopsies showed lichenoid reactions at nickel contact sites, indicating an immune response.

    Area of Science:

    • Oral Medicine
    • Dermatology
    • Immunology

    Background:

    • Nickel is a common contact allergen, frequently causing allergic contact dermatitis.
    • Intraoral exposure to allergens can lead to oral mucosal reactions, though diagnosis can be challenging.

    Observation:

    • Intraoral patch testing was conducted on three subjects using maxillary acrylic plates with 66% nickel test pieces for 48 hours.
    • Clinical examination revealed minimal signs at the contact sites post-testing.

    Findings:

    • Biopsies from intraoral nickel contact sites demonstrated lichenoid reactions in subjects sensitive to nickel.
    • Control site biopsies showed only minor, non-specific inflammatory changes, highlighting the localized reaction to nickel.

    Implications:

    Related Experiment Videos

    • Intraoral patch testing can be a valuable diagnostic tool for identifying nickel allergy in oral mucosa.
    • Lichenoid reactions observed in biopsies suggest a cell-mediated immune response to intraoral nickel exposure.
    • Further research is warranted to establish standardized protocols for intraoral patch testing and understand the long-term effects.