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Recent Trends in Heart Failure and Concomitant Depression, A Retrospective Study
Ovie Okorare1, Daniel Ubokudum2, Unwam Jumbo2
1Department of Internal Medicine, Vassar Brothers Medical Center, Nuvance Health, Poughkeepsie, NY.
Current Problems in Cardiology
|October 6, 2023
Summary
Hospitalizations for heart failure patients with depression increased from 2016-2020. While in-hospital mortality varied, associated in-hospital events like stroke and respiratory failure significantly rose.
Area of Science:
- Cardiology
- Psychiatry
- Health Services Research
Background:
- Depression is linked to worse outcomes in heart failure patients, including higher rehospitalization, reduced function, and mortality.
- Understanding trends in heart failure patients with depression is crucial for improving care and prognosis.
Purpose of the Study:
- To analyze recent trends in hospitalizations and in-hospital mortality for heart failure patients with co-occurring depression in the United States.
- To identify changes in associated in-hospital events and costs over a five-year period.
Main Methods:
- Utilized data from the Nationwide Inpatient Sample (NIS) from 2016 to 2020.
- Included adult patients (≥18 years) with heart failure and depression diagnoses.
- Analyzed in-hospital mortality, in-hospital events (stroke, arrhythmia, respiratory failure), length of stay, and costs using International Classification of Disease 10th edition codes.
Main Results:
- Total hospitalizations for heart failure patients with depression increased from 126,317 to 147,798 annually.
- Average hospitalization costs rose significantly ($34,954 to $44,151), while median hospital stay remained stable (4-5 days).
- Rates of in-hospital events, including stroke, arrhythmia, and respiratory failure, significantly increased (P < 0.0001).
Conclusions:
- Hospitalizations for heart failure patients with depression are rising, accompanied by escalating costs.
- Despite stable overall mortality trends, the incidence of critical in-hospital events has significantly increased, highlighting a growing burden of complications.
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