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Breastfeeding Duration and Cardiometabolic Health during Adolescence: A Longitudinal Analysis
Abeer A Aljahdali1, Alejandra Cantoral2, Karen E Peterson3
1Department of Clinical Nutrition, King Abdulaziz University, Jeddah, Saudi Arabia; Department of Nutritional Sciences, University of Michigan, Ann Arbor, MI.
Insights
Breastfeeding duration showed sex-specific effects on adolescent body composition in Mexican youth. However, evidence for protection against cardiometabolic health issues was limited, suggesting further research is needed.
Area of Science:
- Pediatric Endocrinology
- Cardiovascular Health
- Nutritional Science
Background:
- Breastfeeding is recognized for its health benefits, but its long-term impact on cardiometabolic health requires further investigation.
- Understanding the relationship between breastfeeding duration and adolescent health outcomes is crucial for public health initiatives.
Purpose of the Study:
- To examine the longitudinal association between breastfeeding duration and cardiometabolic health indicators in children and adolescents.
- To explore potential sex-specific differences in these associations.
Main Methods:
- A longitudinal study followed 634 Mexican children and adolescents (aged 10-21 years) from a birth cohort.
- Breastfeeding duration was prospectively recorded, and cardiometabolic risk factors, body composition, and biomarkers were assessed over time.
- Sex-stratified linear mixed-effects models were employed to analyze the data, adjusting for relevant covariates.
Main Results:
- Median breastfeeding duration was 7 months. Boys with 5 months of breastfeeding showed lower fat mass and higher lean and skeletal muscle mass compared to those with 2 months.
- A positive linear trend between breastfeeding duration and trunk lean mass was observed in girls.
- No significant associations were found between breastfeeding duration and other cardiometabolic risk factors.
Conclusions:
- Breastfeeding duration demonstrated sex-specific associations with body composition in Mexican adolescents.
- Limited evidence supports a protective effect of breastfeeding against impaired cardiometabolic health during adolescence in this population.
- Further longitudinal research with detailed breastfeeding assessments is recommended.
Objective:
To investigate the longitudinal association between breastfeeding duration and cardiometabolic health, using repeated measures study design among children and adolescents.
Study Design:
This study included 634 offsprings aged 10 to 21 years (52% female) from the Early Life Exposure in Mexico to Environmental Toxicants birth cohort followed up to four time points during adolescence. Breastfeeding duration was prospectively quantified using questionnaires during early childhood. Cardiometabolic risk factors, body composition, and weight-related biomarkers were assessed as outcomes during adolescent follow-up visits. Sex-stratified linear mixed-effects models were used to model the association between quartiles of breastfeeding duration and outcomes, adjusting for age and additional covariates.
Results:
Median breastfeeding duration was 7 months (minimum = 0, maximum = 36). Boys in the second quartile (median breastfeeding = 5 months) had lower total fat mass % (β (SE) -3.2 (1.5) P = .037), and higher lean mass % (3.1 (1.6) P = .049) and skeletal muscle mass % (1.8 (0.8) P = .031) compared with the reference group (median breastfeeding = 2 months). A positive linear trend between breastfeeding duration and trunk lean mass % (0.1 (0.04) P = .035) was found among girls. No association was found with other cardiometabolic indicators.
Conclusion:
Despite sex-specific associations of breastfeeding duration with body composition, there was a lack of substantial evidence for the protective effects of breastfeeding against impaired cardiometabolic health during adolescence among Mexican youth. Further longitudinal studies with a robust assessment of breastfeeding are recommended.
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