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Updated: Jul 14, 2025
A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products
Published on: October 4, 2019
[Research progress on chemical constituents and pharmacological activities of halogenated sesquiterpenes from natural
Hua-Wei Lyu1, Ji-Ye Zhang1, Hai Cai1
1Key Laboratory of Efficient Exploitation and Utilization of Deep Blue Fishery Resources of Zhejiang Province, Key Laboratory of Traditional Chinese Medicine for Innovative R&D and Digital Intelligent Manufacturing of Traditional Chinese Medicine Great Health Products of Zhejiang Province, College of Pharmaceutical Science, Zhejiang University of Technology Huzhou 313000, China.
Abstract:
Halogenated sesquiterpenes are important derivatives of sesquiterpenes, referring to chemical components of sesquiterpenes that contain halogens such as chlorine, bromine, and iodine. Halogenated sesquiterpenes have attracted attention from researchers in China and abroad because of their diverse structures, unique halogen elements, and extensive pharmacological activities. Studies have shown that halogenated sesquiterpenes exhibit significant antimicrobial, anti-inflammatory, anticancer, insecticidal, hypoglycemic, and enzyme inhibitory activities. In order to better explore the potential pharmaceutical value of halogenated sesquiterpenes, this paper reviewed the structural characteristics and pharmacological activities of halogenated sesquiterpenes in the past two decades, aiming to provide references for further research and development of this class of compounds.
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