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Related Experiment Videos

Suprofen-induced acute renal failure.

N E Henann, J R Morales

    Drug Intelligence & Clinical Pharmacy
    |November 1, 1986
    PubMed
    Summary
    This summary is machine-generated.

    A young adult experienced acute flank pain and reversible kidney failure after taking suprofen. Kidney function normalized after discontinuing the medication, highlighting a potential adverse drug reaction.

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    Area of Science:

    • Nephrology
    • Clinical Pharmacology

    Background:

    • Nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly used for pain relief.
    • NSAIDs can cause renal adverse effects, particularly in susceptible individuals.

    Observation:

    • A case of acute flank pain and renal failure in a young adult is reported.
    • The patient had taken three doses of suprofen, an NSAID.

    Findings:

    • Elevated blood urea nitrogen and serum creatinine levels indicated significant renal impairment.
    • Renal function returned to normal after cessation of suprofen therapy, demonstrating reversibility.

    Implications:

    • This case highlights the potential for suprofen to induce acute kidney injury.
    • Clinicians should be aware of NSAID-associated nephrotoxicity and monitor renal function in patients using these drugs.