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The Japanese Breast Cancer Society Clinical Practice Guidelines for systemic treatment of breast cancer, 2022 edition

Mitsuo Terada1, Aki Ito2, Yuichiro Kikawa3

  • 1Department of Breast Surgery, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.

Breast Cancer (Tokyo, Japan)
|October 7, 2023
PubMed

Insights

The 2022 Japanese Breast Cancer Society guidelines offer updated systemic treatment recommendations. These evidence-based updates focus on efficacy and safety, incorporating findings from Japanese clinical trials.

Area of Science:

  • Oncology
  • Clinical Practice Guidelines
  • Breast Cancer Treatment

Background:

  • The Japanese Breast Cancer Society (JBCS) initiated an update process in 2018.
  • Guidelines are crucial for standardizing breast cancer care.

Purpose of the Study:

  • To present the 2022 edition of the JBCS Clinical Practice Guidelines for systemic breast cancer treatment.
  • To highlight key updates and practice-changing recommendations based on recent evidence.

Main Methods:

  • Systematic reviews (quantitative and qualitative) of evidence were conducted for 33 clinical questions (CQs).
  • Outcomes including efficacy and safety were assessed.
  • Recommendations were finalized through a voting process by committee members.

Main Results:

  • The 2022 guidelines include 12 background questions (BQs), 33 CQs, and 20 future research questions (FRQs).
  • Eight selected CQs represent significant updates, including novel practice-changing information.
  • Recommendations are based on evidence, with a focus on Japanese clinical trials.

Conclusions:

  • The updated guidelines provide current, evidence-based recommendations for systemic breast cancer treatment.
  • These guidelines incorporate recent advancements and trial data, particularly from Japan.
  • The JBCS aims to improve patient outcomes through these updated clinical practice guidelines.
Keywords:
Breast cancerGuidelinesJBCSSystemic treatment

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