[Septicemia causative organisms 1983-1985. The results of a multicenter study]
Deutsche Medizinische Wochenschrift (1946)
|December 5, 1986
Summary
This study analyzed 8,999 bloodstream infection (BSI) pathogens from 8,500 patients. Gram-negative rods and gram-positive cocci were the most common BSI pathogens, with distinct patterns in children versus adults.
Area of Science:
- Microbiology
- Infectious Diseases
- Epidemiology
Context:
- Multi-center study conducted across West Germany, West Berlin, and Austria over two years.
- Involved analysis of 8,999 bloodstream infection (BSI) pathogens from 8,500 patients.
- Demographic data including patient sex and age distribution were collected.
Purpose:
- To characterize the spectrum of pathogens causing BSIs.
- To investigate age-related incidence patterns of BSIs.
- To compare pathogen profiles between pediatric and adult populations.
- To assess antibiotic susceptibility through minimum inhibitory concentration (MIC) determination.
Summary:
- Gram-negative rods (49%) and gram-positive cocci (45%) were the predominant BSI pathogens.
- BSIs showed a bimodal age distribution, with high incidence in neonates and a peak in the seventh decade of life.
- Significant differences in pathogen spectrum were observed between children and adults.
- Minor variations in pathogen distribution were noted based on hospital type and ward.
Impact:
- Provides crucial epidemiological data on BSIs in Central Europe.
- Highlights the need for age-specific treatment strategies for BSIs.
- Informs antibiotic stewardship and empirical treatment guidelines.
- Contributes to understanding evolving patterns of bacterial resistance.
