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Skeletal muscle extracellular matrix structure under applied deformation observed using second harmonic generation

Niamh Hennessy1, Ciaran Simms1

  • 1Trinity Centre for Biomedical Engineering, Department of Mechanical, Manufacturing and Biomedical Engineering, Parsons Building, Trinity College Dublin, College Green, Dublin 2, Ireland.

Acta Biomaterialia
|October 7, 2023
PubMed
Summary

Second Harmonic Generation (SHG) microscopy visualizes the extracellular matrix (ECM) in skeletal muscle. This technique reveals how collagen fibers reorganize under tension and compression, improving biomechanical models.

Keywords:
Extracellular matrixPerimysiumSecond harmonic generationSkeletal muscleTension-compression

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