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Identifying Coronary Artery Calcification on Non-gated Computed Tomography Scans
Published on: August 28, 2018
The gut microbiota and coronary artery calcification in Japanese men
Yukiko Okami1, Hisatomi Arima2, Keiko Kondo3
1NCD Epidemiology Research Center, Shiga University of Medical Science, Otsu, Japan..
Background:
The gut microbiota differs between patients with coronary artery disease (CAD) and healthy controls; however, it currently remains unclear whether these differences exist prior to the onset of CAD. We herein investigated the gut microbiota associated with subclinical coronary artery calcification (CAC) in a Japanese population.
Methods:
A total of 663 Japanese men were enrolled in this cross-sectional study. Computed tomography and gut microbiology tests were performed, and CAC scores were calculated using the Agatston method. Participants were categorized into 4 groups based on their CAC scores: CAC = 0, 0
Results:
The mean age of participants was 68.4 years (46-83 years). The numbers of participants in CAC = 0, 0
Conclusions:
The gut microbiota significantly differed from the phylum to genus level in a manner that was dependent on CAC scores, even before the onset of CAD.
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