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Diagnosis of equine pituitary pars intermedia dysfunction.
Allison J Stewart1, Joanne L Ireland2, Andy E Durham3
1The University of Queensland, Gatton, QLD 4343, Australia.
Veterinary Journal (London, England : 1997)
|October 7, 2023
Summary
Accurate diagnosis of equine pituitary pars intermedia dysfunction (PPID) is crucial for lifelong treatment. Combining clinical judgment with basal adrenocorticotrophic hormone (ACTH) testing offers high diagnostic accuracy for PPID in horses.
Area of Science:
- Veterinary Medicine
- Equine Endocrinology
- Diagnostic Accuracy Studies
Background:
- Equine pituitary pars intermedia dysfunction (PPID) is a prevalent endocrine disorder in aging horses.
- Lifelong treatment necessitates precise diagnosis, yet no single laboratory test is perfect.
- Diagnostic test accuracy is influenced by population characteristics.
Conclusions:
- Accurate PPID diagnosis in horses relies on a multifaceted approach.
- Basal ACTH testing is a practical and accurate primary diagnostic tool when used judiciously.
- TRH stimulation testing serves as a valuable secondary test for complex or subtle PPID cases.

