Related Experiment Video
Updated: Jul 14, 2025

Engineered Vascularized Muscle Flap
Published on: January 11, 2016
Vascularized fibular flap and custom-made synthesis in post-traumatic ulnar diaphyseal pseudarthrosis: a case report
Filippo Zanotti1, Gabriele Molteni2, Umberto Lavagnolo3
1Hand Surgery Unit, University Hospital of Verona, Verona, Italy.
Insights
This case study highlights the successful treatment of complex post-traumatic ulnar pseudarthrosis using a vascularized fibular graft combined with 3D-planned custom implants. This innovative approach offers a viable solution for challenging bone reconstructions.
Area of Science:
- Orthopedic Surgery
- Regenerative Medicine
- Biomedical Engineering
Background:
- Ulnar shaft fractures can lead to complications, particularly in revision cases with anatomical distortion.
- Vascularized fibular grafts are advantageous for recurrent pseudarthrosis, but require patient-specific fixation in revision surgeries.
Observation:
- A 38-year-old woman presented with post-traumatic ulnar pseudarthrosis and forearm deformity after multiple failed previous treatments.
- Previous attempts using avascular bone grafts and standard fixation resulted in graft and hardware failure.
- The patient underwent reconstruction with a vascularized fibular graft and a 3D-planned, custom-made plate and screws due to complex anatomy and poor bone quality.
Findings:
- The vascularized fibular graft achieved union at both proximal and distal ulnar junctions within 6-8 months.
- Postoperative follow-up showed no inflammatory reactions or rejection.
- Functional outcomes included pain reduction and preservation of range of motion.
Implications:
- The combination of vascularized bone grafting and 3D planning offers a promising strategy for complex post-traumatic reconstructions.
- Customized implants and surgical guides derived from 3D models enhance precision in revision surgeries.
- This case demonstrates the potential of personalized reconstructive techniques for challenging orthopedic cases.
Background:
Although isolated fractures of the ulnar shaft are considered common and relatively benign injuries, numerous complications can arise especially in the context of suboptimal care pathways. For pediatric patients, however, there is no single indication of the surgical approach. In the context of the management of these complications, it is known that the vascularized fibular graft has numerous advantages and indications in the treatment of recurrent pseudarthrosis. However, in revision surgery the frequent occurrence of anatomical subversions requires the use of fixation means adapted to the individual patient. We present a clinical case of an adult patient suffering from post-traumatic ulnar pseudarthrosis treated with autologous vascularized fibula grafts and 3D-planned custom-made plate.
Case Presentation:
A 38-year-old Ivorian woman came to our attention with a painful nonunion of the ulnar shaft and significant dysmorphism of the left forearm, with shortening and flexion of the limb as an outcome of unspecified road trauma in childhood. No alterations of the nerve compartment were reported. As far as detectable, she had undergone autologous bone grafting and implantation of questionable synthetic means, without acute treatment. Since we evaluated the patient (2012), we have performed two debridement surgeries, associated with autologous avascular bone graft from the iliac crest and plate fixation (2012 and 2014). In both cases, rupture of the fixation media was observed. In 2021, the pseudarthrosis was treated with a vascularized fibular bone graft. The subverted radius and ulna anatomy and poor bone quality required patient-specific reconstruction of the pseudarthrosic ulna from a 3D scan and the production of custom-made plate and screws, supported by the creation of special guides for drilling and by optimizing the positioning of screws with preoperative digital models. In the postoperative period, regular follow-up visits with X-rays evaluations were performed at 1, 3 and 6 months after surgery. No inflammatory reactions or local rejection were found. The fibula graft healed at the proximal ulnar junction six months after the operation while it took eight months to heal at the distal junction. Functionally, we observed a pain reduction and a range-of-motion preservation.
Conclusions:
The multiple failures of diaphyseal reconstruction with avascular bone grafts have forced the indication to the vascularized fibular flap. This case is a unique experience but we believe that the association between vascularized bone graft and the potential for customization through 3D planning represents a valid surgical potentiality in complex cases of post-traumatic reconstruction.
More Related Videos
08:20A Reliable and Reproducible Critical-Sized Segmental Femoral Defect Model in Rats Stabilized with a Custom External Fixator
Published on: March 24, 2019
09:01Treatment of Ankle Osteoarthritis with Total Ankle Replacement Through a Lateral Transfibular Approach
Published on: January 24, 2018