Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Changes in Skin Color: Clinical Perspectives01:14

Changes in Skin Color: Clinical Perspectives

2.0K
The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
2.0K
Skin Diseases and Disorders01:23

Skin Diseases and Disorders

3.9K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
3.9K
Skin Cancer01:30

Skin Cancer

4.2K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
4.2K
The Effect of Aging on Tissues01:19

The Effect of Aging on Tissues

2.1K
Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...
2.1K
Reticular Dermis01:15

Reticular Dermis

2.6K
The papillary and reticular dermis are the two layers of the dermis. They are made of connective tissue with fibers of collagen extending from one to the other, making the border between the two somewhat indistinct. The dermal papillae extending into the epidermis belong to the papillary layer, whereas the dense collagen fiber bundles below belong to the reticular layer.
Reticular Layer
Underlying the papillary layer is the much thicker reticular layer, composed of dense, irregular connective...
2.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Project ODIN: advancing environmental genomic surveillance for public health across sub-Saharan Africa.

The Lancet. Microbe·2026
Same author

Trends in funding for coronavirus vaccine research and development: implications for preparedness against future coronavirus threats.

NPJ vaccines·2026
Same author

Long-Term Effects of Maternal Glycemic Measures in Pregnancy and Offspring Adverse Glycemic Outcomes: Results from the TEAM Study.

American journal of perinatology·2026
Same author

Impact, barriers, and facilitators of blood culture diversion devices to reduce blood culture contamination and improve patient safety: a scoping review.

The Journal of hospital infection·2026
Same author

Identifying Wellness Priorities in Nursing Roles Across Rural America.

The Journal of nursing administration·2026
Same author

Diffuse Large B-Cell Lymphoma Transdifferentiating Into Histiocytic Sarcoma: Case Report + Systematic Review.

Journal of cutaneous pathology·2025
Same journal

Correlation of Clinical and Histopathological Features With Anti-Desmoglein Antibody Profile in Pemphigus Patients.

International journal of dermatology·2026
Same journal

Clinicopathological Challenge: A Painful Violaceous Reticulated Patch.

International journal of dermatology·2026
Same journal

Editor's Highlights-August 2026.

International journal of dermatology·2026
Same journal

Preliminary Validation of the Early Sacroiliitis Screening Tool (ESHST) for Identifying Hidradenitis Suppurativa Patients at High Risk of Spondyloarthritis.

International journal of dermatology·2026
Same journal

Efficacy of Intralesional Bevacizumab Versus Intralesional Triamcinolone Acetonide Injection in the Treatment of Keloids: A Randomized Clinical Trial.

International journal of dermatology·2026
Same journal

Evaluation of Intralesional Bleomycin and Triamcinolone Acetonide in the Treatment of Keloids: A Prospective, Randomized, Open-Label, Comparative Study.

International journal of dermatology·2026
See all related articles

Related Experiment Video

Updated: Jul 14, 2025

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus
05:38

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus

Published on: May 16, 2025

119

Considerations in geriatric dermatopathology.

Ashley A Brent1, Elizabeth Mancuso2, Emily Smith1,3

  • 1Department of Pathology, Michigan Medicine, University of Michigan, Ann Arbor, MI, USA.

International Journal of Dermatology
|October 9, 2023
PubMed
Summary
This summary is machine-generated.

This review covers geriatric dermatopathology, focusing on specimen handling and age-related skin changes. It highlights common pitfalls and future research directions in aging skin conditions.

More Related Videos

Resolving Water, Proteins, and Lipids from In Vivo Confocal Raman Spectra of Stratum Corneum through a Chemometric Approach
09:32

Resolving Water, Proteins, and Lipids from In Vivo Confocal Raman Spectra of Stratum Corneum through a Chemometric Approach

Published on: September 26, 2019

7.2K
The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
11:39

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

Published on: July 11, 2013

39.0K

Related Experiment Videos

Last Updated: Jul 14, 2025

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus
05:38

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus

Published on: May 16, 2025

119
Resolving Water, Proteins, and Lipids from In Vivo Confocal Raman Spectra of Stratum Corneum through a Chemometric Approach
09:32

Resolving Water, Proteins, and Lipids from In Vivo Confocal Raman Spectra of Stratum Corneum through a Chemometric Approach

Published on: September 26, 2019

7.2K
The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
11:39

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

Published on: July 11, 2013

39.0K

Area of Science:

  • Dermatology
  • Pathology
  • Gerontology

Background:

  • Geriatric dermatopathology presents unique challenges in specimen handling and interpretation.
  • Aging skin exhibits specific histopathologic changes and is prone to photoaging-related lesions.

Purpose of the Study:

  • To provide a comprehensive overview of geriatric dermatopathology considerations.
  • To discuss specimen collection, reporting, histopathologic changes, and interpretation pitfalls in the elderly population.

Main Methods:

  • Review of existing literature on geriatric dermatopathology.
  • Analysis of histopathologic changes associated with aging and photoaging.
  • Identification of common interpretation pitfalls and special cases.

Main Results:

  • Key considerations for specimen collection and reporting in geriatric patients are outlined.
  • Histopathologic features of aging skin and photoaging lesions are detailed.
  • Common interpretation pitfalls, including overinterpretation and pigmentary changes, are discussed.

Conclusions:

  • Geriatric dermatopathology requires careful attention to specimen quality and clinical context.
  • Understanding age-related changes and common pitfalls is crucial for accurate diagnosis.
  • Further research is needed to address special cases and advance the field.