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Updated: Jul 14, 2025

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement
Published on: December 11, 2017
All-cause procedural readmissions following transcatheter aortic valve replacement
Paige Newell1, Hoda Javadikasgari1, Mehida Rojas-Alexandre1
1Division of Cardiac Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass.
Subsequent procedural readmissions are common after transcatheter aortic valve replacement (TAVR) but do not impact patient survival. These interventions, both cardiac and non-cardiac, can be safely pursued when necessary following TAVR.
Area of Science:
- Cardiovascular Medicine
- Interventional Cardiology
- Health Services Research
Background:
- Transcatheter aortic valve replacement (TAVR) eligibility is expanding to patients with longer life expectancies.
- Subsequent procedures after TAVR are increasingly common and necessitate evaluation.
Purpose of the Study:
- To investigate the incidence and outcomes of patients undergoing procedural readmissions after TAVR.
- To determine if these readmissions affect long-term survival.
Main Methods:
- Retrospective analysis of 1092 patients undergoing TAVR from 2012-2019.
- Evaluation of mortality and hospital readmissions for procedures lasting over 1 day.
- Survival analysis using Cox proportional hazard models and competing risk analysis.
Main Results:
- 20% of patients experienced 244 procedural readmissions (260 procedures) within a median follow-up of 34 months.
- Cardiac procedures included pacemaker implantation and PCI; non-cardiac included orthopedic and GI interventions.
- Procedural readmissions were not associated with a survival penalty across surgical risk groups (HR 1.25, P=.17).
Conclusions:
- Procedural interventions post-TAVR are frequent, often occurring within the first year.
- Subsequent procedural readmissions do not appear to confer a survival disadvantage.
- Necessary procedures after TAVR should be pursued to address patient needs.
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