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Published on: October 28, 2021
Simultaneous infection with Fusarium proliferatum and Prototheca wickerhamii localized at different body sites
1Department of Medical Mycology, Institute of Dermatology, Chinese Academy of Medical Science and Peking Union Medical College, No.12, Jiangwangmiao Street, Xuanwu District, Nanjing, 210042, China.
Abstract:
2012 Elsevier Ltd. All rights reserved. Subcutaneous infections caused by two unusual fungi are rare. Here we report an elderly woman with long-term glucocorticoid use who was infected with Fusarium proliferatum on the right dorsum of the hand presenting with a verrucous plaque and Prototheca wickerhamii on the left dorsum of the hand presenting with geographic ulcers with erythematous plaques. The diagnosis was made through histopathological examination of skin samples and fungal culture, with identification through molecular examination. She was successfully treated with voriconazole.
Insights
This study reports a rare case of subcutaneous fungal infections in an elderly woman using glucocorticoids. She was successfully treated for infections caused by Fusarium proliferatum and Prototheca wickerhamii with voriconazole.
Area of Science:
- Mycology
- Dermatology
- Infectious Diseases
Background:
- Subcutaneous fungal infections are uncommon, particularly those caused by unusual fungal species.
- Long-term glucocorticoid use can predispose individuals to opportunistic infections.
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