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Leucocytoclastic Vasculitis Presenting as Bilateral Ulcerative Keratitis: A Case Report
Hui Feng1, Shang Li1, Ying Jie1
1Beijing Ophthalmology and Visual Sciences Key Laboratory, Beijing Tongren Eye Center, Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
Clinical Medicine Insights. Case Reports
|October 9, 2023
Summary
Leukocytoclastic vasculitis (LCV) can rarely cause ocular issues. This case highlights successful surgical treatment for peripheral ulcerative keratitis (PUK) secondary to LCV.
Area of Science:
- Ophthalmology
- Dermatology
- Rheumatology
Background:
- Leukocytoclastic vasculitis (LCV) is an immune-mediated small artery disease.
- LCV typically presents with purpuric papules on the limbs, with ocular manifestations being rare.
Observation:
- A 59-year-old male with a history of LCV (diagnosed 6 years prior) presented with corneal perforation in his left eye.
- He later developed peripheral ulcerative keratitis (PUK) in his right eye, characterized by pain, redness, and photophobia.
Findings:
- The patient underwent conjunctival flap surgery for both corneal perforation and PUK.
- Surgical intervention successfully resolved symptoms and stabilized the eye condition in both instances.
Implications:
- This case represents the first reported instance of PUK secondary to LCV.
- Successful surgical management of PUK associated with LCV is demonstrated, offering a viable treatment option.

