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Updated: Jul 14, 2025

Author Spotlight: Integrating Mechanical and Biological Analysis in Tendinopathy Research
Published on: March 1, 2024
Flexor Tendon Rupture Secondary to Gout.
Jeremy V Lynn1, Amy L Strong1, Kevin C Chung1
1Section of Plastic Surgery, Department of Surgery, University of Michigan Medical School, Ann Arbor, Michigan.
Gout can cause rare flexor tendon ruptures in the hand due to monosodium urate crystal deposition. Surgical reconstruction and medication management are key for treating this uncommon complication of gout.
Area of Science:
- Rheumatology
- Orthopedic Surgery
- Hand Surgery
Background:
- Extra-articular deposition of monosodium urate crystals is a known manifestation of gout.
- Gouty infiltration of flexor tendons in the hand leading to rupture is exceptionally rare.
Purpose of the Study:
- To report a rare case of flexor tendon rupture in the hand caused by gouty infiltration.
- To discuss the management and treatment of this unusual presentation of gout.
Main Methods:
- A case report detailing a patient with gouty infiltration of flexor tendons in the right middle finger.
- Surgical intervention involving a two-stage flexor tendon reconstruction and pulley reconstruction.
- Pharmacological management including febuxostat and prednisone.
Main Results:
- The patient experienced rupture of both the flexor digitorum profundus and flexor digitorum superficialis tendons.
- Successful two-stage reconstruction was performed, addressing the extensive gouty infiltration and pulley damage.
- Medications were used to manage crystal deposition and prevent flares during treatment.
Conclusions:
- Tendon rupture secondary to gouty infiltration should be considered in patients with a history of gout presenting with tendon insufficiency.
- A multidisciplinary approach involving surgery and medication is crucial for managing this rare condition.
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