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Acral lentiginous melanoma with multiple bone metastasis: case report
Pei Ting Chen1, Kapilkumar Manvar1, Rashid Chaudhry1
1Division of Hematology/Oncology, Brookdale University Hospital Medical Center, Brooklyn, New York, USA.
The Pan African Medical Journal
|October 9, 2023
Summary
Acral lentiginous melanoma (ALM), a rare skin cancer, can present with bone metastases even without other organ involvement. This case highlights a unique presentation in an elderly African American male.
Area of Science:
- Dermatology
- Oncology
- Pathology
Background:
- Acral lentiginous melanoma (ALM) is a rare subtype of cutaneous melanoma, accounting for less than 5% of cases.
- ALM typically affects non-white populations and is often diagnosed at later stages.
- Common melanoma metastasis sites include skin, subcutaneous tissue, lungs, liver, brain, and bone.
Observation:
- A unique case of ALM is presented in an 84-year-old African American male.
- The initial lesion was located on the plantar aspect of the right fifth toe.
- The patient presented with multiple bone metastases as the primary manifestation.
Findings:
- The patient's ALM presented with extensive bone metastases.
- No other organ involvement was detected at the time of diagnosis.
- This presentation is unusual as bone metastases typically occur in widespread disease.
Implications:
- This case underscores the importance of considering ALM in differential diagnoses for unexplained bone metastases, particularly in at-risk populations.
- Early detection and prompt management of ALM are crucial for improving patient outcomes.
- Further research into the metastatic patterns of ALM may be warranted.
