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Updated: Jul 14, 2025

Two-photon Calcium Imaging in Neuronal Dendrites in Brain Slices

Two-photon Calcium Imaging in Neuronal Dendrites in Brain Slices

Published on: March 15, 2018

Seizure Event Detection Using Intravital Two-Photon Calcium Imaging Data.

Matthew A Stern^1,2, Eric R Cole^1,2,3, Robert E Gross^2,3

¹Authors Contributed Equally.

Biorxiv : the Preprint Server for Biology

|October 9, 2023

Summary

Researchers developed an automated algorithm to detect seizure events using calcium imaging. This tool precisely identifies cell recruitment and seizure wavefronts, aiding epilepsy research.

Keywords:

EEG Epilepsy GECI Multiphoton Optical Imaging Signal Processing

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Last Updated: Jul 14, 2025

Two-photon Calcium Imaging in Neuronal Dendrites in Brain Slices

Two-photon Calcium Imaging in Neuronal Dendrites in Brain Slices

Published on: March 15, 2018

Author Spotlight: An Innovative Approach to Neural Electrical Stimulation Using Calcium Imaging

Author Spotlight: An Innovative Approach to Neural Electrical Stimulation Using Calcium Imaging

Published on: August 18, 2023

Author Spotlight: Insights into the Techniques and Findings of Recent Advancements in Epilepsy Research

Author Spotlight: Insights into the Techniques and Findings of Recent Advancements in Epilepsy Research

Published on: October 13, 2023

Area of Science:

Neuroscience
Computational Biology
Epilepsy Research

Background:

Genetic cellular calcium imaging offers novel insights into neuronal microcircuitry and seizure activity.
Existing electrophysiology methods for seizure activity lack comparable calcium imaging techniques.

Conclusions:

The developed algorithm enables accurate cell recruitment detection in calcium imaging data.
This tool will assist researchers in studying seizure dynamics and epilepsy.
Facilitates a deeper understanding of microcircuit-level interactions during seizure activity.