Related Experiment Video
Updated: Jul 14, 2025

Diagnosis and Surgical Treatment of Human Brucellar Spondylodiscitis
Published on: May 23, 2021
Vertebral osteomyelitis secondary to Streptococcus cristatus infection
Helen Tran1, Angela Ai1, Oscar E Gallardo-Huizar1
1Department of Medicine, Olive View-UCLA Medical Center, Sylmar, CA, United States.
Abstract:
A 66-year-old male with a history of low back pain was found to have discitis and osteomyelitis. Biopsy and PCR testing revealed Streptococcus cristatus infection. This bacteria does not typically cause disease, and only a few cases in the literature have reported it to cause infection in the bones or joints. This case illustrates that vertebral osteomyelitis with a rare causative agent, S. cristatus, is possible and can be identified with PCR. Treatment typically requires long-term antibiotics tailored to the causative agent for a minimum of 6 weeks and can sometimes include surgical management.
Insights
A rare Streptococcus cristatus infection caused discitis and osteomyelitis in a 66-year-old man. Polymerase chain reaction (PCR) identified this unusual pathogen, highlighting its potential for bone infections.
Area of Science:
- Infectious Diseases
- Microbiology
- Orthopedics
Background:
- Discitis and osteomyelitis are serious spinal infections.
- Bacterial causes are typically common pathogens.
- Streptococcus cristatus is an uncommon cause of infection.
Observation:
- A 66-year-old male presented with low back pain, diagnosed with discitis and osteomyelitis.
- Biopsy and PCR testing identified Streptococcus cristatus as the causative agent.
- This bacterium rarely infects bone or joint tissues.
Findings:
- Vertebral osteomyelitis can be caused by rare bacteria like Streptococcus cristatus.
- Polymerase chain reaction (PCR) is effective in identifying unusual pathogens.
- Treatment involves targeted, long-term antibiotics (minimum 6 weeks) and potentially surgery.
Implications:
- This case expands the known spectrum of vertebral osteomyelitis pathogens.
- Highlights the importance of PCR in diagnosing infections with rare organisms.
- Informs clinical management strategies for uncommon spinal infections.
More Related Videos
09:09Treatment with Vancomycin Loaded Calcium Sulphate and Autogenous Bone in an Improved Rabbit Model of Bone Infection
Published on: March 14, 2019
04:19Minimally Invasive Treatment for Thoracolumbar Burst Fracture Using Sagittal Alignment Screws and A Trauma Reduction Device
Published on: November 8, 2024
Related Concept Videos
Acute Pyelonephritis II: Diagnostic Studies and Management
Endocarditis II: Clinical Features of Infective Endocarditis
Bacterial Phylum Spirochaetes
Endocarditis III: Medical Management