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Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
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Prevented harm and cost avoidance with pharmacist intervention while utilizing a discharge medication reconciliation

Abigail M Hoffman1, Jennifer L Walls2, Amanda Prusch2

  • 1Department of Pharmacy, Wellspan York Hospital, York, PA, USA.

American Journal of Health-System Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists
|October 9, 2023
PubMed
Summary

Pharmacist interventions using discharge medication reconciliation tools prevented significant patient harm and avoided substantial costs. These crucial interventions, particularly with high-risk medications, demonstrate clear value in healthcare settings.

Keywords:
cost avoidancedischargedischarge toolmedication reconciliationpharmacistprevented harm

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Area of Science:

  • Health Economics
  • Patient Safety
  • Clinical Pharmacy

Background:

  • Medication errors are a significant source of preventable patient harm.
  • Effective medication reconciliation is vital for safe patient transitions, especially at discharge.

Purpose of the Study:

  • To quantify the cost avoidance and prevented harm resulting from pharmacist interventions during discharge medication reconciliation.
  • To assess the financial impact of pharmacist-led medication reconciliation processes.

Main Methods:

  • A retrospective chart review identified pharmacist-initiated discharge medication reconciliation interventions.
  • Discrepancies were categorized using the National Coordinating Council for Medication Error Reporting and Prevention (NCC MERP) system.
  • Cost avoidance was calculated based on intervention type and associated risk.

Main Results:

  • Pharmacists performed 190 interventions, potentially avoiding $46,958 to $231,032 in costs.
  • Interventions involving high-risk medications accounted for $33,920 to $147,203 in cost avoidance.
  • Top cost-avoiding medication classes included insulin, antithrombotics, and opioids.

Conclusions:

  • Pharmacist-led discharge medication reconciliation effectively prevents patient harm.
  • These interventions lead to significant cost avoidance, highlighting their value in healthcare systems.