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Related Concept Videos

Pathophysiology of Peptic Ulcer Disease: Injurious Factors01:22

Pathophysiology of Peptic Ulcer Disease: Injurious Factors

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Peptic ulcers are sores on the stomach's inner lining and the upper small intestine, which are the result of disruptions in the mucosal layer that houses parietal cells which produce gastric acid, and chief cells which secrete pepsinogen.
In the antrum region, G cells secrete the gastrin hormone that binds to gastrin-cholecystokinin-B (CCK2) receptors on parietal and enterochromaffin-like (ECL) cells in the fundic glands. Simultaneously, the vagus nerve releases acetylcholine, which binds...
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Gastritis-II: Pathophysiology01:17

Gastritis-II: Pathophysiology

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Gastritis is marked by disruption of the mucosal barrier that usually protects the stomach tissue from digestive juices and manifests in acute and chronic forms.
In acute gastritis, the gastric mucosa becomes swollen and red and undergoes superficial erosion. Superficial ulceration may lead to bleeding.
In chronic gastritis, persistent or repeated insults lead to chronic inflammatory changes and, eventually, thinning or atrophy of the gastric tissue.
Gastritis can stem from various causes, each...
357
Peptic Ulcer Disease I: Introduction01:30

Peptic Ulcer Disease I: Introduction

184
Peptic Ulcer Disease (PUD) is characterized by mucosal excavation in the esophagus, stomach, pylorus, or duodenum. It can manifest as acute or chronic based on the extent and duration of mucosal involvement.
An acute ulcer, marked by superficial erosion and minimal inflammation, swiftly resolves upon identifying and addressing the underlying cause. In contrast, a chronic ulcer persists, potentially eroding through the muscular wall and forming fibrous tissue.
Peptic ulcers can also be...
184
Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies01:28

Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies

151
Peptic ulcer disease (PUD) presents with diverse symptoms depending on the location and severity of the ulcer. Clinical manifestations of peptic ulcer include dull pain and a burning sensation in the mid-epigastric region.
Few clinical manifestations differentiate gastric ulcers from duodenal ulcers. Distinctions in the location, timing, and pain relief are crucial for healthcare providers in differentiating between gastric and duodenal ulcers during clinical assessments.
151
Gastritis-I: Introduction and Types01:27

Gastritis-I: Introduction and Types

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Gastritis, defined by the inflammation or irritation of the stomach lining or gastric mucosa, manifests in several distinct forms: acute, chronic, reactive, and a specific subtype known as autoimmune metaplastic atrophic gastritis.
Acute gastritis presents as a sudden inflammation triggered by various stressors to the stomach lining, such as exposure to corrosive agents, local irritants like aspirin and other NSAIDs, alcohol consumption, radiation therapy, physical trauma, severe burns, sepsis,...
495
Gastritis III: Clinical Manifestations and Management01:23

Gastritis III: Clinical Manifestations and Management

308
The clinical manifestations of gastritis can vary depending on the cause and type of gastritis, but some common symptoms may include the following.
Clinical manifestations of acute gastritis
The patient with acute gastritis may have a rapid onset of symptoms, such as epigastric pain or discomfort, dyspepsia, anorexia, hiccups, or nausea and vomiting, which can last from a few hours to a few days. Erosive or hemorrhagic gastritis may cause bleeding, which may manifest as blood in vomit or as...
308

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Idiopathic Gastric Antral Ulcers.

Masaya Iwamuro1, Takehiro Tanaka2, Seiji Kawano1

  • 1Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Japan.

Internal Medicine (Tokyo, Japan)
|October 9, 2023
PubMed
Summary

A case study highlights a chronic idiopathic gastric antral ulcer in a Japanese woman, emphasizing the condition

Keywords:
Helicobacter pyloridiopathic ulceresophagogastroduodenoscopygastric ulcer

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Area of Science:

  • Gastroenterology
  • Internal Medicine
  • Pathology

Background:

  • Gastric antral ulcers can present with chronic, recurring patterns.
  • Idiopathic gastric ulcers are often overlooked in clinical practice.
  • Helicobacter pylori infection is a common cause, but other etiologies must be excluded.

Purpose of the Study:

  • To present a case of chronic idiopathic gastric antral ulcer.
  • To illustrate the diagnostic process for this rare condition.
  • To provide a visual reference of chronological endoscopic findings.

Main Methods:

  • Clinical case presentation.
  • Endoscopic examination and biopsy.
  • Laboratory blood tests to rule out other causes.

Main Results:

  • A Japanese woman with a six-year history of recurring gastric antral ulcers.
  • Biopsy and lab results excluded H. pylori and other known ulcer etiologies.
  • Diagnosis of idiopathic gastric antral ulcer was confirmed.

Conclusions:

  • Idiopathic gastric antral ulcer is a diagnosis of exclusion.
  • Chronic recurrence can occur without identifiable causes.
  • Endoscopic imaging is crucial for diagnosis and monitoring.