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Related Experiment Video

Updated: Jul 14, 2025

A Polyaniline-based Sensor of Nucleic Acids
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Detection of Biomarkers through Functionalized Polymers.

Litzy L García-Faustino1, Stephen M Morris2, Steve J Elston2

  • 1School of Engineering and Sciences, Tecnológico de Monterrey, Ave. Eugenio Garza Sada 2501, Monterrey, NL, 64849, Mexico.

Small Methods
|October 9, 2023
PubMed
Summary

Functionalized porous polymers offer new ways to detect biomarkers. These materials change physically to modulate optical signals, enabling biocompatible sensors for in situ measurements.

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Area of Science:

  • Materials Science
  • Polymer Chemistry
  • Biomedical Engineering

Background:

  • Growing interest in functionalized porous polymers for advanced sensor applications.
  • Nanostructured materials (hydrogels, nanosheets, nanopores) are key for incorporating functional groups.
  • Functionalized polymers' physical changes are crucial for modulating optical signals.

Purpose of the Study:

  • Provide an overview of publication trends in functionalized polymers for sensors.
  • Highlight functional groups that induce measurable physical deformations.
  • Categorize materials by detection targets (proteins, carbohydrates, ions, DNA).

Main Methods:

  • Literature review of functionalized polymer sensor research.
  • Analysis of materials based on their functional groups and detection mechanisms.
Keywords:
biomarkersfunctionalizationpolymerssensors

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  • Categorization of sensors by target analytes.

    • Main Results:

    • Functionalized polymers enable physical changes for optical signal modulation.
    • Biocompatible sensors for in situ biomarker measurement are feasible.
    • Diverse detection targets including proteins, carbohydrates, ions, and DNA are addressed.

    Conclusions:

    • Functionalized porous polymers are promising for developing novel sensors.
    • Understanding structure-property relationships is key for sensor design.
    • This review serves as a reference for future functionalized polymer sensor development.