Use of Surgical Adjuvants Does Not Decrease Recurrence of Aneurysmal Bone Cysts in Surgical Intervention With...

Area of Science:

• Orthopedic Surgery
• Pediatric Oncology
• Skeletal Tumors

Background:

• Aneurysmal bone cysts (ABCs) are benign, active bone tumors common in children.
• Intralesional curettage is a standard treatment, often with surgical adjuvants.
• Recurrence rates and influencing factors require further investigation.

Purpose of the Study:

• To determine if surgical adjuvants impact recurrence rates in pediatric ABCs.
• To analyze recurrence based on patient age, sex, and physeal contact.

Main Methods:

• Retrospective review of 129 pediatric patients with histologically confirmed ABCs (2004-2020).
• Data collected on demographics, lesion location, treatment, and recurrence.
• Statistical analysis compared recurrence rates with and without adjuvant use, and by age, sex, and physeal contact.

Main Results:

• No significant difference in recurrence rates between patients who received surgical adjuvants and those who did not (25.3% vs. 23.7%).
• Physeal contact was not significantly associated with recurrence (P = 0.146).
• Patients younger than 6 years old had a significantly higher recurrence rate (66.7%) compared to older children (21.7%, P = 0.007).

Conclusions:

• Surgical adjuvants do not appear to influence the recurrence risk of pediatric ABCs treated with curettage.
• Younger age (≤6 years) is a significant risk factor for ABC recurrence.
• Physeal contact and sex were not found to be significant predictors of recurrence.