Microbial-host-isozyme: unveiling a new era in microbiome-host interaction.
Lei Miao1, Herbert Tilg2, Ming-Hua Zheng3,4
1Department of Gastroenterology, the Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.
Gut Microbes
|October 10, 2023
Summary
Microbial-Host isozymes (MHIs) are bacterial enzymes impacting host health. Researchers found bacterial DPP4 degrades GLP-1, explaining varied drug responses and offering new metabolic disorder treatments.
Area of Science:
- Microbiology
- Metabolic disorders
- Enzymology
Background:
- Microbiota-host interactions are crucial for metabolic health.
- Bacterial enzymes can influence host physiology.
- Understanding these interactions is key to treating metabolic diseases.
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