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Experimental study on physical exercise in diabetes: pathophysiology and therapeutic effects
Giuseppe Messina1, Anna Alioto2, Maria Chiara Parisi3
1Department of Human Sciences and Promotion of the Quality of Life, San Raffaele University, Rome. giuseppe.messina@uniroma5.it.
European Journal of Translational Myology
|October 11, 2023
Summary
Regular exercise significantly benefits type II diabetes management, improving blood sugar and BMI more effectively in active individuals compared to sedentary ones. This highlights exercise as a crucial, complementary therapy for diabetes control.
Area of Science:
- Endocrinology
- Sports Medicine
- Metabolic Diseases
Background:
- Diabetes mellitus type II is a chronic condition.
- A sedentary lifestyle is a significant risk factor for obesity and type II diabetes.
- Exercise interventions can potentially mitigate diabetes complications.
Purpose of the Study:
- To evaluate the positive and negative effects of exercise on type II diabetic patients.
- To compare outcomes between active and sedentary diabetic individuals.
- To assess changes in pathophysiology and key health markers over 3 and 6 months.
Main Methods:
- A study involving 90 participants (male and female) with type II diabetes, aged 45.
- Participants were divided into a sedentary group (Group A, n=50) and an active group (Group B, n=40).
- Evaluation included anthropometric parameters and blood chemistry values.
Main Results:
- Improvements were more pronounced in the active group (Group B) compared to the sedentary group (Group A).
- Blood sugar (glycemic values) and Body Mass Index (BMI) showed the most significant improvements.
- Cholesterol and HbA1c levels decreased, though at a slower rate than glycemic values and BMI.
Conclusions:
- Exercise demonstrates therapeutic and preventive benefits for type II diabetes.
- Personalized exercise protocols, developed through multidisciplinary collaboration (diabetologist, sports physician, kinesiologist/trainer), are recommended.
- Physical activity serves as an essential adjunct therapy to insulin treatment.
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