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Experimental documentation of presence of purinergic receptors at human atria
Abstract:
Our experimental data suggest the likelihood that there is a purinergic inhibition on human atria; it appears that inhibition is mediated via P1/Ri (A-1/Ri) and P-2 receptors. Adenosine and ATP produced inhibitory effects on chronotropism and inotropism via P1/Ri (A-1/Ri) and P-2 receptors respectively.