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Mitral Regurgitation I: Introduction01:20

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Mitral regurgitation is characterized by the backward circulation of blood from the left ventricle to the left atrium during systole, a phase of the cardiac cycle when the heart contracts and pumps blood out of the chambers. This abnormal flow occurs primarily due to the dysfunction of the mitral valve or its supporting structures, which include the mitral leaflets, chordae tendineae, annulus, and papillary muscles.Etiology and Mechanisms:Primary Mitral Regurgitation: This type arises from...
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Coronary Circulation01:21

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The heart, an organ critical to survival, gets nourishment not from the blood it pumps but from a separate circulation system known as coronary circulation. This is the shortest circulation in the body and is responsible for supplying the heart with the nutrients it needs to function effectively.
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Mitral Stenosis I: Introduction01:22

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Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
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The human heart is made up of three layers of tissue that are surrounded by the pericardium, a membrane that protects and confines the heart. The outermost layer, closest to the pericardium, is the epicardium. The pericardial cavity separates the pericardium from the epicardium. Beneath the epicardium is the myocardium, the middle layer, and the endocardium, the innermost layer. There are four chambers of the heart: the right atrium, the right ventricle, the left atrium, and the left ventricle.
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Updated: Jul 13, 2025

Morphological and Functional Assessment of the Right Ventricle Using 3D Echocardiography
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Morphological and Functional Assessment of the Right Ventricle Using 3D Echocardiography

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Double outlet right ventricle.

Yolandee Bell-Cheddar1,2, William A Devine3, Carlos-Eduardo Diaz-Castrillon4

  • 1Division of Pediatric Cardiac Critical Care, UPMC Children's Hospital of Pittsburgh , Pittsburgh, PA, United States.

Frontiers in Pediatrics
|October 11, 2023
PubMed
Summary
This summary is machine-generated.

This review covers double outlet right ventricle (DORV), detailing its history, anatomy, and current medical and surgical treatments. It provides a comprehensive overview for understanding and managing this congenital heart defect.

Keywords:
atrioventricular septal defectdouble outlet right ventriclegeneticspreoperative managementsurgical managementventricular septal defect

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Area of Science:

  • Cardiology
  • Pediatric Cardiology
  • Congenital Heart Disease

Background:

  • Double outlet right ventricle (DORV) is a complex congenital heart defect.
  • Understanding DORV's varied presentations is crucial for effective management.

Purpose of the Study:

  • To provide a comprehensive review of double outlet right ventricle (DORV).
  • To cover the historical context, anatomical variations, and diagnostic approaches.
  • To outline current medical and surgical management strategies.

Main Methods:

  • Literature review of existing studies on DORV.
  • Synthesis of information on embryology, anatomy, and pathophysiology.
  • Analysis of treatment outcomes from various surgical techniques.

Main Results:

  • Detailed description of DORV morphology and anatomical classifications.
  • Overview of diagnostic tools including echocardiography and MRI.
  • Summary of evolving surgical repair strategies and their outcomes.

Conclusions:

  • DORV management requires a multidisciplinary approach.
  • Surgical intervention is tailored to individual patient anatomy.
  • Continued research is needed to improve long-term outcomes for DORV patients.