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Anterior Segment Organ Culture Platform for Tracking Open Globe Injuries and Therapeutic Performance
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Characteristics, Etiological Factors, and Visual Outcomes of Pediatric Open Globe Injuries in Central Saudi Arabia: A

Huda Al Ghadeer1, Rajiv Khandekar2,3

  • 1Emergency Department, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.

Clinical Ophthalmology (Auckland, N.Z.)
|October 11, 2023
PubMed

Insights

Open globe injuries (OGIs) in children are a major cause of unilateral blindness. While standard treatment improves vision, many young patients still struggle to regain functional sight after pediatric eye trauma.

Area of Science:

  • Ophthalmology
  • Pediatric Ophthalmology
  • Trauma Surgery

Background:

  • Open globe injuries (OGIs) pose a significant threat to vision in children.
  • Understanding the characteristics and causes of pediatric OGIs is crucial for effective management.
  • Tertiary eye hospitals play a vital role in managing complex pediatric eye trauma cases.

Purpose of the Study:

  • To investigate the characteristics, etiological factors, and visual outcomes of open globe injuries (OGIs) in children.
  • To analyze visual acuity changes following management in pediatric OGI cases.
  • To identify factors influencing visual outcomes in children with OGIs.

Main Methods:

  • A hospital-based cohort study was conducted in 2021.
  • Included children aged ≤16 years with OGIs classified using the Birmingham Eye Trauma Terminology.
  • Recorded patient demographics, injury type, cause, and visual acuity (UCVA and BCVA) at presentation and one year post-management.

Main Results:

  • 664 eyes with OGI were analyzed; 69.6% of patients were boys, with a median age of 5.1 years.
  • Metallic objects (29.4%), glass (15.4%), and fireworks (9.4%) were primary causes of injury.
  • Significant visual improvement was observed post-management (p < 0.001), with 52% achieving a two-line BCVA improvement, 45% showing no change, and 1.5% experiencing deterioration.

Conclusions:

  • Open globe injuries are a leading cause of unilateral blindness in children.
  • Standard treatment protocols for pediatric OGIs lead to improved visual outcomes.
  • Despite interventions, achieving normal functional vision remains a challenge for many children with OGIs.
Abstract

Keywords:
childinjuriesocularpediatricstrauma

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