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Synthesis of a Borylated Ibuprofen Derivative Through Suzuki Cross-Coupling and Alkene Boracarboxylation Reactions
Published on: November 30, 2022
Rex S C Charman1, Josie A Hobson1, Ross A Jackson1
1Department of Chemistry, University of Bath, Claverton Down, Bath, BA2 7AY, UK.
This study introduces novel copper boryl compounds, (6-Dipp)CuB(OMe)2 and (6-Dipp)CuB(OMe)NMe2, synthesized via sigma-bond metathesis. These compounds demonstrate reactivity in C-B bond insertions and catalytic CO2 deoxygenation.
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