Volume assured pressure support mode use for non-invasive ventilation in pediatrics
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Updated: Jul 13, 2025

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Published on: February 14, 2022
Nisha Cithiravel1, Lena Xiao2, Jenny Shi2
1Department of Respiratory Therapy, The Hospital for Sick Children, Toronto, Canada.
Insights
Volume Assured Pressure Support (VAPS) ventilation is increasingly used in pediatric patients, including those with congenital central hypoventilation syndrome and neuromuscular diseases. This review guides clinicians on VAPS initiation, settings, and troubleshooting for children.
Area of Science:
- Pediatric Pulmonology
- Mechanical Ventilation
- Sleep Medicine
Background:
- Volume Assured Pressure Support (VAPS) is gaining traction in pediatric care, expanding beyond its traditional adult applications.
- Its use is growing in pediatric populations with conditions like obesity hypoventilation syndrome, congenital central hypoventilation syndrome, and neuromuscular diseases (e.g., Duchenne muscular dystrophy, spinal muscular atrophy).
Approach:
- This review provides a comprehensive guide for pediatric pulmonologists and sleep physicians on VAPS.
- It covers initiation methods, specific ventilator settings, and identification of suitable pediatric patient groups.
- The article details ventilator titration using polysomnography and interpretation of ventilator data downloads.
- Common challenges and troubleshooting for VAPS machine alarms are also addressed.
Key Points:
- Familiarity with VAPS is crucial for pediatric specialists due to its expanding use.
- The review offers practical guidance on VAPS implementation and management in children.
- Effective troubleshooting of VAPS alarms is essential for patient safety.
Conclusions:
- This review aims to enhance the understanding and application of VAPS in pediatric respiratory care.
- It equips clinicians with the knowledge to optimize VAPS therapy for diverse pediatric conditions.
- Improved VAPS management can lead to better outcomes for children requiring ventilatory support.
Abstract:
There has been increasing interest in utilizing volume assured pressure support (VAPS) modes of ventilation for children, which historically had only been favored in adult populations. In addition to patients with obesity hypoventilation syndrome, newer pediatric populations for which it has recently been prescribed include congenital central hypoventilation syndrome and children with neuromuscular disease such as Duchenne muscular dystrophy and spinal muscular atrophy. Given its expanding use in pediatrics, greater familiarity with VAPS is essential for pediatric pulmonologists and sleep physicians. This review article will highlight methods of initiation for this mode, specific ventilator settings, discussion of suitable pediatric patient populations, ventilator titrations via formal polysomnograms and detailed ventilator data downloads specific interpretation. Finally, common challenges to be aware of and how to troubleshoot relevant machine alarms will be reviewed.
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