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Published on: June 5, 2012
The identification of Pseudomonas cepacia and its occurrence in clinical material
Abstract:
During the 19 year period ending December 1984, 4840 strains of Gram-negative non-fermentative bacteria were submitted to the National Collection of Type Cultures for identification. Of these, 195 strains (4.0% of the total) were identified as Pseudomonas cepacia which demonstrates both that the species is regularly encountered in clinical material in the UK and that several laboratories have experienced difficulty in identifying the organism. The sources from which the 195 strains were isolated are reported and also the characteristics by which the species may be recognized. The clinical significance of Ps. cepacia is reviewed, and the resistance of this species to disinfectants and antimicrobial agents commonly used to treat pseudomonas infections is discussed to underline the necessity for the precise identification of Ps. cepacia.
Insights
Pseudomonas cepacia is frequently found in clinical samples in the UK, yet often misidentified by labs. Precise identification is crucial due to its resistance to common treatments.
Area of Science:
- Clinical Microbiology
- Bacteriology
Background:
- Gram-negative non-fermentative bacteria are common in clinical settings.
- Accurate identification of bacterial species is essential for effective treatment.
Purpose of the Study:
- To report the frequency and sources of Pseudomonas cepacia isolates in the UK.
- To outline identification characteristics for Pseudomonas cepacia.
- To review the clinical significance and resistance patterns of Pseudomonas cepacia.
Main Methods:
- Analysis of 4840 bacterial strains submitted for identification over 19 years (ending Dec 1984).
- Identification of 195 strains as Pseudomonas cepacia.
- Review of isolation sources and phenotypic characteristics.
Main Results:
- Pseudomonas cepacia constituted 4.0% (195/4840) of identified strains.
- The organism was regularly encountered in UK clinical material.
- Laboratories frequently experienced difficulties in identifying Pseudomonas cepacia.
Conclusions:
- Pseudomonas cepacia is a significant clinical isolate in the UK.
- Accurate identification is necessary due to the organism's resistance to common disinfectants and antimicrobial agents.
- Standard identification methods may be insufficient for routine laboratory diagnosis of Pseudomonas cepacia.
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