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Postoperative Opioid Prescribing Practices and Patient Opioid Utilization in Pediatric Orthopaedic Surgery Patients
Marguerite A Mullen1, Kang Woo Kim1, Michaela Procaccini2
1Warren Alpert Medical School of Brown University.
Insights
Pediatric orthopaedic surgery patients often do not use their entire opioid prescription, with many using zero doses. This study highlights variations in opioid prescribing and low utilization rates, informing safer practices.
Area of Science:
- Pediatric Orthopaedic Surgery
- Pain Management
- Public Health
Background:
- The national opioid epidemic necessitates reviewing opioid prescription necessity.
- Adult studies show patients often don't use full opioid prescriptions; this trend is suspected in children.
- Limited data exists on pediatric opioid utilization post-surgery.
Purpose of the Study:
- To investigate opioid prescription volume and postoperative utilization rates in pediatric orthopaedic surgery patients.
- To identify factors influencing opioid prescribing and usage in this population.
Main Methods:
- Identified pediatric patients (<18 years) undergoing orthopaedic surgery.
- Collected patient demographics and opioid prescription data.
- Surveyed parents/guardians on pain, opioid use, and remaining doses via diaries or phone interviews.
- Analyzed data using Wilcoxon rank-sum, t-tests, Pearson correlation, and logistic regression.
Main Results:
- 280 patients' prescription data collected; utilization data from 102.
- Upper extremity fractures received fewer opioid doses (P=0.036).
- Higher BMI correlated with more prescribed opioid doses (R²=0.647, P<0.001).
- Mean opioid utilization rate was 22.37%; 50.6% used zero doses.
- 96.2% used opioids for ≤5 days; most families hadn't disposed of excess medication.
Conclusions:
- Significant variations in opioid prescribing exist based on patient and procedure specifics.
- Pediatric orthopaedic patients show low overall opioid utilization but with procedural variations.
- Findings can guide opioid prescribing and promote safe disposal education for pediatric patients.
Introduction:
Amid a national opioid epidemic, it is essential to review the necessity of opioid prescriptions. Research in adults has demonstrated patients often do not use their entire postoperative opioid prescription. Limited data suggest that the trend is similar in children. This study investigated the prescription volume and postoperative utilization rate of opioids among pediatric orthopaedic surgery patients at our institution.
Methods:
We identified pediatric patients (ages below 18 y old) who presented to our institution for operating room intervention from May 24, 2021, to December 13, 2021. Patient demographics and opioid prescription volume were recorded. Parents and guardians were surveyed by paper "opioid diary" or phone interview between postoperative days 10 to 15, assessing pain level, opioid use, and plans for remaining opioid doses. Wilcoxon rank-sum test, Independent t test, and Pearson correlation were used for the analysis of continuous variables. Multivariable logistic regression was used to control for patient demographic variables while analyzing opioid usage relationships.
Results:
Prescription volume information was collected for 280 patients during the study period. We were able to collect utilization information for 102 patients (Group 1), whereas the remaining 178 patients contributed only prescription volume data (Group 2). Patients with upper extremity fractures received significantly fewer opioid doses at discharge compared with other procedure types ( P =0.036). Higher BMI was positively correlated with more prescribed opioid doses ( R2 =0.647, P <0.001). The mean opioid utilization rate was 22.37%. A total of 50.6% of patients prescribed opioids at discharge used zero doses. A total of 96.2% of patients used opioids for 5 days or less. Most families had not disposed of excess medication by postoperative day 10.
Conclusions:
We found significant differences in opioid prescribing practices based on patient and procedure-specific variables. In addition, although our pediatric orthopaedic surgery patients had low overall rates of postoperative opioid utilization, there was significant variation in opioid use among procedure types. These results provide insights that can guide opioid prescribing practices for pediatric orthopaedic patients and promote patient education to ensure safe opioid disposal.
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