Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Increased Body Temperature01:25

Increased Body Temperature

687
A body temperature above  38°C  (100.4 °F) is known as fever or pyrexia, and a person with fever is termed 'febrile.' Typically, the hypothalamus, a part of the brain that acts as the body's thermostat, regulates body temperature through a thermoregulatory setpoint. It receives signals from cold and warm thermal receptors throughout the body and adjusts the body's temperature accordingly. Fever occurs when this hypothalamic setpoint is altered, usually in...
687
Seizures: Classification01:13

Seizures: Classification

378
Epilepsy is primarily characterized by unpredictable seizures, either provoked by an identifiable factor, such as injury or illness, or unprovoked, occurring spontaneously without apparent cause.
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:
378
Types of Fever01:25

Types of Fever

385
Fever can be triggered by several factors, including infections, nervous system disorders, certain cancers, blood diseases like leukemia, embolism, thrombosis, heatstroke, dehydration, surgical trauma, crushing injuries, and allergic reactions.
Here are the different types of fever:
385
Patterns of Fever01:26

Patterns of Fever

2.6K
Before understanding the types and patterns of fever, it is essential to know its phases.
2.6K
Methods of reducing fever01:22

Methods of reducing fever

678
The signs and symptoms of fever include hot and dry skin, flushed face, thirst, muscle aches, anorexia, headache, tachycardia, tachypnea, and fatigue. Elevated body temperature is reduced using two methods: pharmacological and nonpharmacological. Proper identification and treatment of the root cause of a fever is of utmost importance.
Pharmacological Methods of Reducing Fever:
678
Antiepileptic Drugs: Modulators of Neurotransmitter Release Mediated by SV2A Protein01:20

Antiepileptic Drugs: Modulators of Neurotransmitter Release Mediated by SV2A Protein

318
Antiepileptic drugs, such as levetiracetam (Keppra) and brivaracetam (Briviact), have emerged as crucial tools in managing epilepsy. These medications exert their therapeutic effects by targeting the synaptic vesicle protein SV2A, a transmembrane glycoprotein primarily found in the brain.
SV2A is a transmembrane glycoprotein located predominantly in the brain, modulating the release of neurotransmitters for neuronal communication. Both levetiracetam and brivaracetam exhibit a high affinity for...
318

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Childhood-Onset Huntington's Disease-Like Presentation of SCA17 with Intermediate Repeats, A Case Report.

Cerebellum (London, England)·2026
Same author

Treatment Practices and Outcomes in Continuous Spike and Wave during Slow Wave Sleep: A Multicenter Collaboration.

The Journal of pediatrics·2021
Same author

Neurodevelopmental mutation of giant ankyrin-G disrupts a core mechanism for axon initial segment assembly.

Proceedings of the National Academy of Sciences of the United States of America·2019
See all related articles

Related Experiment Video

Updated: Jul 13, 2025

A Behavioral Screen for Heat-Induced Seizures in Mouse Models of Epilepsy
06:58

A Behavioral Screen for Heat-Induced Seizures in Mouse Models of Epilepsy

Published on: July 12, 2021

4.9K

Febrile Seizures.

Samantha Biltz, Laura Speltz

    Pediatric Annals
    |October 11, 2023
    PubMed
    Summary

    Febrile seizures (FSs) are common in young children with fever. While most are brief and harmless, some children experience recurrence, and a few face an increased epilepsy risk.

    Area of Science:

    • Pediatrics
    • Neurology

    Background:

    • Febrile seizures (FSs) are the most frequent seizure type in children aged 6 months to 5 years.
    • They are associated with elevated body temperature (≥100.4°F) and often have a family history.
    • FSs are categorized as simple, complex, or febrile status epilepticus.

    Purpose of the Study:

    • To review the definition, classification, risk factors, and outcomes of febrile seizures.
    • To highlight the impact of FSs on caregivers and healthcare utilization.
    • To emphasize the need for effective patient and family education.

    Main Methods:

    • Literature review and synthesis of existing research on febrile seizures.
    • Analysis of classification criteria, recurrence rates, and long-term sequelae.
    • Examination of associated psychological factors and healthcare trends.

    More Related Videos

    Author Spotlight: Advancing Pediatric Epilepsy Surgery in Children Through Novel Biomarkers and Enhanced Localization
    09:57

    Author Spotlight: Advancing Pediatric Epilepsy Surgery in Children Through Novel Biomarkers and Enhanced Localization

    Published on: September 20, 2024

    2.7K
    Interictal High Frequency Oscillations Detected with Simultaneous Magnetoencephalography and Electroencephalography as Biomarker of Pediatric Epilepsy
    10:22

    Interictal High Frequency Oscillations Detected with Simultaneous Magnetoencephalography and Electroencephalography as Biomarker of Pediatric Epilepsy

    Published on: December 6, 2016

    20.4K

    Related Experiment Videos

    Last Updated: Jul 13, 2025

    A Behavioral Screen for Heat-Induced Seizures in Mouse Models of Epilepsy
    06:58

    A Behavioral Screen for Heat-Induced Seizures in Mouse Models of Epilepsy

    Published on: July 12, 2021

    4.9K
    Author Spotlight: Advancing Pediatric Epilepsy Surgery in Children Through Novel Biomarkers and Enhanced Localization
    09:57

    Author Spotlight: Advancing Pediatric Epilepsy Surgery in Children Through Novel Biomarkers and Enhanced Localization

    Published on: September 20, 2024

    2.7K
    Interictal High Frequency Oscillations Detected with Simultaneous Magnetoencephalography and Electroencephalography as Biomarker of Pediatric Epilepsy
    10:22

    Interictal High Frequency Oscillations Detected with Simultaneous Magnetoencephalography and Electroencephalography as Biomarker of Pediatric Epilepsy

    Published on: December 6, 2016

    20.4K

    Main Results:

    • Most FSs are simple, self-limiting, and last under 10 minutes.
    • Approximately one-third of children experience recurrent FSs.
    • While most children have no long-term issues, febrile status epilepticus increases epilepsy risk.

    Conclusions:

    • Febrile seizures are common but typically benign, though recurrence is possible.
    • Caregiver anxiety and "fever phobia" necessitate improved patient education and reassurance.
    • Further research is needed to identify safe and effective prophylactic treatments for FSs.