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Voriconazole-induced psychosis in rhino-orbital invasive aspergillosis

H Swarna Rekha1,2, Sabharisan Paramasivam3, Kalaiarasi Raja3

  • 1Department of Psychiatry, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.

BMJ Case Reports
|October 11, 2023
PubMed

Insights

Voriconazole, an antifungal drug, can cause rare psychosis as an adverse drug reaction (ADR). This case highlights the importance of recognizing and managing this iatrogenic effect in patients with invasive aspergillosis.

Area of Science:

  • Mycology
  • Pharmacology
  • Neurology

Background:

  • Invasive aspergillosis presents a significant clinical challenge.
  • Voriconazole is a first-line triazole antifungal agent for invasive aspergillosis, Cryptococcus neoformans, and Candida infections.
  • Adverse drug reactions (ADRs) to voriconazole, though uncommon, require clinical awareness.
Keywords:
Ear, nose and throat/otolaryngologyPsychiatry

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