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Published on: May 9, 2022
STITCH enabled molecular interaction of glycrhizzin with peri-implant microbiota
Karthickraj Selladurai1, Sahana Selvaganesh1, Vishnu Priya Veeraraghavan1
1Department of Implantology1, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Medical and Technical Sciences, Saveetha University, Chennai 600077, India.
Abstract:
Glycyrrhizin is present in the root extract of the licorice plant used for various conditions, including gastric ulcers. Therefore, it is of interest to document the STITCH enabled molecular interaction of glycrhizzin with peri-implant microbiota. The peri implant pathogens includes Aggregatibacter actinomycetemcomitans (D7S-1), Centipeda periodontii, Campylobacter gracilisi, Fusobacterium nucleatumi, Slackia exigua, Prevotella intermedia, Tannerella forsythia, Staphylococcus aureus, Bacteroides fragilis, and Bacteroides fragilis. Hence, a user-defined query was used to conduct analysis on the provided bacterial strains whose molecular data available in the STITCH database. Thus, we used the STITCH tool to examine protein interactions and the VirulentPred tool to assess pathogenicity using the known molecular data on glycrhizzin and peri implant pathogens. Data shows that glycyrrhizin interacts with peri implant pathogens.
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