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Updated: Jul 13, 2025
Neisseria meningitidis Infection of Induced Pluripotent Stem-Cell Derived Brain Endothelial Cells
Published on: July 14, 2020
Erratum: Neisseria meningitidis Infection of Induced Pluripotent Stem-Cell Derived Brain Endothelial Cells
Abstract:
An erratum was issued for: Neisseria meningitidis Infection of Induced Pluripotent Stem-Cell Derived Brain Endothelial Cells Larvae. The Authors section was updated from: Leo M. Endres1 Alexandra Schubert-Unkmeir1 Brandon J. Kim1,2 1Institute for Hygiene and Microbiology, University of Würzburg 2Department of Biological Sciences, University of Alabama to: Leo M. Endres1 Sarah F. Hathcock2 Alexandra Schubert-Unkmeir1 Brandon J. Kim1,2 1Institute for Hygiene and Microbiology, University of Würzburg 2Department of Biological Sciences, University of Alabama.
Insights
An erratum has been issued for a study on Neisseria meningitidis infection. The author list has been updated to include Sarah F. Hathcock.
Area of Science:
- Microbiology
- Neuroscience
- Stem Cell Biology
Background:
- Neisseria meningitidis is a significant human pathogen.
- Brain endothelial cells are crucial for the blood-brain barrier.
- Induced pluripotent stem cells (iPSCs) offer a model for studying human cell types.
Purpose of the Study:
- To investigate the interaction of Neisseria meningitidis with iPSC-derived brain endothelial cells.
- To understand the mechanisms of meningococcal infection in a relevant cellular model.
Main Methods:
- Generation of brain endothelial cells from induced pluripotent stem cells.
- Infection of these cells with Neisseria meningitidis.
- Microscopic and molecular analyses to assess infection.
Main Results:
- The study examined Neisseria meningitidis infection dynamics.
- The interaction with iPSC-derived brain endothelial cells was analyzed.
Conclusions:
- The findings contribute to understanding Neisseria meningitidis pathogenesis.
- This research highlights the utility of iPSC-derived models in infectious disease research.
