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Evidence for a magnesium- and ATP-dependent calcium extrusion pump in dog erythrocytes
Biochimica Et Biophysica Acta
|June 13, 1979
Abstract:
Intact dog erythrocytes, whose Ca2+ permeability had been increased with A23187 still maintained intracellular Ca2+ below electrochemical equilibrium indicating that they could extrude Ca2+. This extrusion required no Na+ gradient but apparently depended on intracellular ATP and Mg2+ suggesting that it was mediated by an ATP-fuelled Ca2+ pump.