Incidence of hydrocephalus following decompressive craniectomy for ischaemic stroke: A systematic review and meta-analysis
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Updated: Oct 21, 2026

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Published on: October 15, 2021
Christopher Dillon Ovenden1, Dwarkesh Dharmendra Barot2, Aashray Gupta3
1Department of Neurosurgery, Royal Adelaide Hospital, Adelaide, Australia; Discipline of Surgery, University of Adelaide, Adelaide, Australia.
Insights
Hydrocephalus is common after decompressive craniectomy for malignant stroke, but most patients do not need cerebrospinal fluid diversion. This systematic review clarifies complication rates for better patient counseling.
Area of Science:
- Neurosurgery
- Neurology
- Critical Care Medicine
Background:
- Decompressive craniectomy (DC) is a critical intervention for malignant ischemic stroke.
- The incidence of ventriculomegaly post-DC for stroke is not well-established.
- Understanding hydrocephalus rates is crucial for patient management.
Conclusions:
- Hydrocephalus is a frequent complication after decompressive craniectomy for malignant stroke.
- A small proportion of patients require permanent cerebrospinal fluid diversion.
- Awareness of these rates is essential for appropriate clinical counseling.
Objective:
Decompressive craniectomy (DC) following malignant ischaemic stroke is a potentially life-saving procedure. Event rates of ventriculomegaly following DC performed in this setting remain poorly defined. Accordingly, we performed a systematic review to determine the incidence of hydrocephalus and the need for cerebrospinal fluid (CSF) diversion following DC for malignant stroke.
Methods:
MEDLINE, EMBASE and Cochrane libraries were searched from database inception to 17 July 2021. Our search strategy consisted of "Decompressive Craniectomy", AND "Ischaemic stroke", AND "Hydrocephalus", along with synonyms. Through screening abstracts and then full texts, studies reporting on rates of ventriculomegaly following DC to treat ischaemic stroke were included for analysis. Event rates were calculated for both of these outcomes. A risk of bias assessment was performed to determine the quality of the included studies.
Results:
From an initial 1117 articles, 12 were included following full-text screening. All were of retrospective design. The 12 included studies reported on 677 patients, with the proportion experiencing hydrocephalus/ventriculomegaly being 0.38 (95% CI: 0.24, 0.53). Ten studies incorporating 523 patients provided data on the need for permanent CSF diversion, with 0.10 (95% CI: 0.07, 0.13) requiring a shunt. The included studies were overall of high methodological quality and rigour.
Conclusion:
Though hydrocephalus is relatively common following DC in this clinical setting, only a minority of patients are deemed to require permanent CSF diversion. Clinicians should be aware of the incidence of this complication and counsel patients and families appropriately.
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