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Biomolecules based hydrogels and their potential biomedical applications: A comprehensive review
Fatima Ijaz1, Hafiz Muhammad Tahir1, Shaukat Ali1
1Department of Zoology, Government College University Lahore, Pakistan.
International Journal of Biological Macromolecules
|October 12, 2023
Summary
Biomolecule-based hydrogels offer versatile, tunable drug delivery systems for biomedical applications. Further research is needed to fully understand their cross-linking mechanisms for cost-effective use.
Area of Science:
- Biomaterials Science
- Polymer Chemistry
- Drug Delivery
Background:
- Increasing demand for biocompatible drug carriers.
- Hydrogels offer tunable structures for controlled drug release at target sites.
- Biological macromolecules like collagen, gelatin, and chitosan are key components.
Purpose of the Study:
- To review biomolecule-based hydrogels and their biomedical applications.
- To highlight the versatility and potential of these advanced biomaterials.
- To identify areas needing further research, such as cross-linking mechanisms.
Main Methods:
- Literature review of biomolecule-based hydrogels.
- Discussion of synthesis and properties of hydrogels.
- Exploration of diverse biomedical applications.
Main Results:
- Hydrogels are 3D polymeric networks with tunable structures.
- Biomolecule-based hydrogels are effective in wound healing, tissue engineering, cosmetics, and contact lenses.
- Understanding of cross-linking and molecular entanglement requires further investigation.
Conclusions:
- Biomolecule-based hydrogels are promising for various biomedical applications.
- Further research into hydrogel mechanisms is crucial for extensive and cost-effective utilization.
- Hydrogels represent a significant advancement in drug delivery technology.
