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Mid-term outcomes after catheter ablation in patients with congenital heart disease
Diogo Faim1, Pedro A Sousa2, Carolina Saleiro2
1Paediatric Cardiology Department, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal.
Insights
Catheter ablation effectively treats cardiac arrhythmias in congenital heart disease (CHD) patients, showing high success rates and a safe profile with minimal recurrence over mid-term follow-up.
Area of Science:
- Cardiology
- Electrophysiology
- Congenital Heart Disease
Background:
- Cardiac arrhythmias pose significant risks for patients with congenital heart disease (CHD).
- Catheter ablation is a potential therapeutic option for managing these arrhythmias.
Purpose of the Study:
- To evaluate the long-term efficacy and safety of catheter ablation in patients diagnosed with congenital heart disease.
Main Methods:
- Retrospective observational study analyzing data from January 2016 to December 2021.
- Included 36 patients with CHD undergoing 44 catheter ablation procedures for various arrhythmias.
- Assessed acute procedural outcomes and long-term recurrence rates.
Main Results:
- Successful ablation of 54 arrhythmias including atrial flutter, atrial tachycardia, atrial fibrillation, and ventricular tachycardia.
- Achieved 93% freedom from arrhythmia recurrence after a median follow-up of 37 months.
- No adverse events were reported, and no recurrence predictors were identified.
Conclusions:
- Catheter ablation demonstrates high mid-term efficacy in managing cardiac arrhythmias in CHD patients.
- The procedure is associated with a favorable safety profile, making it a viable treatment option.
Introduction:
Cardiac arrhythmias are a major concern in patients with CHD. The purpose of this study was to evaluate the long-term outcomes in patients with CHD submitted to catheter ablation.
Materials And Methods:
Observational retrospective study of patients with CHD referred for catheter ablation from January 2016 to December 2021 in a tertiary referral centre. Acute procedural endpoints and long-term outcomes were assessed.
Results:
A total of 44 ablation procedures were performed in 36 CHD patients (55% male, mean age 43 ±3 years). Fifty-four arrhythmias were ablated: 23 cavotricuspid isthmus atrial flutters, 10 atrial re-entrant tachycardias, eight focal atrial tachycardias, eight atrial fibrillations, three atrioventricular re-entrant tachycardias, and two ventricular tachycardias. During a median follow-up time of 37 months (interquartile range 12-51), freedom from arrhythmia recurrence was achieved in 93%, with 1.2 procedures per patient (18% with anti-arrhythmic drugs). There were no adverse events related to catheter ablation. No predictors of recurrence were identified.
Conclusion:
In patients with CHD, catheter ablation presents a high mid-term efficacy while maintaining a safe profile.
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