Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

14
A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
14
Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

21
Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
21
Kidney Transplant III: Nursing Management01:16

Kidney Transplant III: Nursing Management

23
Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
23

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Should pull through be offered to patients with cloacal exstrophy?

Pediatric surgery international·2026
Same author

Can FMN even the playing field? mitochondrial FMN during hypothermic oxygenated perfusion to guide liver utilization.

Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·2026
Same author

Establishing standards for controlled donation after circulatory determination of death in adults: the Bucharest international European Society for Organ Transplantation consensus.

Transplant international : official journal of the European Society for Organ Transplantation·2026
Same author

The Impact of Failed Deceased Donor Kidney Graft Longevity on Mortality.

Progress in transplantation (Aliso Viejo, Calif.)·2026
Same author

Characterizing Trends in Preoperative Workup and Evaluation for Pediatric Patients Needing Gastrojejunostomy Tube Placement.

Journal of laparoendoscopic & advanced surgical techniques. Part A·2026
Same author

Predicting expiration among potential donation after circulatory death donors at 30- and 120-min post extubation.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation·2026
Same journal

Ringer Lactate Versus Hybrid Isotonic/Hypotonic Saline in Delayed Graft Function in Deceased-donor Kidney Transplantation: A Real-world Protocol Change Study.

Transplantation direct·2026
Same journal

Eye Health Among Islet Cell Transplant Recipients With Long-duration Type 1 Diabetes.

Transplantation direct·2026
Same journal

Immunosuppression-free Nonvascularized Rectus Fascia Allotransplantation for Complex Hernia Repair.

Transplantation direct·2026
Same journal

Optimizing Lung Transplant Logistics Using Controlled Hypothermic Preservation to Extend Ischemic Time.

Transplantation direct·2026
Same journal

Impact of Perfusion With Methylene Blue on Perioperative Bleeding in Simultaneous Pancreas and Kidney Transplantation: A Randomized Control Trial.

Transplantation direct·2026
Same journal

Outcomes of Single Pediatric Kidney Grafts: An Experienced Single-center Retrospective Study.

Transplantation direct·2026
See all related articles

Related Experiment Video

Updated: Jul 13, 2025

Normothermic Ex Vivo Kidney Perfusion for the Preservation of Kidney Grafts prior to Transplantation
08:12

Normothermic Ex Vivo Kidney Perfusion for the Preservation of Kidney Grafts prior to Transplantation

Published on: July 15, 2015

19.2K

Assessing Kidney Transplantation Using ECMO-Supported Donors Within a KDPI-Based Allocation System.

Peter J Altshuler1, Devon J Pace1, William A Preston1

  • 1Department of Surgery, Thomas Jefferson University, Philadelphia, PA.

Transplantation Direct
|October 13, 2023
PubMed
Summary
This summary is machine-generated.

Kidney transplants from donors on extracorporeal membrane oxygenation (ECMO) can expand the donor pool. While VA-ECMO kidneys show comparable survival to standard donors, VV-ECMO kidneys have higher graft loss risks.

More Related Videos

Using a Chemical Biopsy for Graft Quality Assessment
05:00

Using a Chemical Biopsy for Graft Quality Assessment

Published on: June 17, 2020

5.2K
Orthotopic Kidney Auto-Transplantation in a Porcine Model Using 24 Hours Organ Preservation And Continuous Telemetry
07:58

Orthotopic Kidney Auto-Transplantation in a Porcine Model Using 24 Hours Organ Preservation And Continuous Telemetry

Published on: August 21, 2020

7.2K

Related Experiment Videos

Last Updated: Jul 13, 2025

Normothermic Ex Vivo Kidney Perfusion for the Preservation of Kidney Grafts prior to Transplantation
08:12

Normothermic Ex Vivo Kidney Perfusion for the Preservation of Kidney Grafts prior to Transplantation

Published on: July 15, 2015

19.2K
Using a Chemical Biopsy for Graft Quality Assessment
05:00

Using a Chemical Biopsy for Graft Quality Assessment

Published on: June 17, 2020

5.2K
Orthotopic Kidney Auto-Transplantation in a Porcine Model Using 24 Hours Organ Preservation And Continuous Telemetry
07:58

Orthotopic Kidney Auto-Transplantation in a Porcine Model Using 24 Hours Organ Preservation And Continuous Telemetry

Published on: August 21, 2020

7.2K

Area of Science:

  • Nephrology
  • Transplantation
  • Cardiopulmonary support

Background:

  • Extracorporeal membrane oxygenation (ECMO) support in organ donors historically raises concerns about graft quality.
  • This study investigates renal allograft transplant outcomes from donors supported by ECMO for non-donation purposes.

Purpose of the Study:

  • To evaluate the safety and efficacy of using renal allografts from ECMO-supported donors for kidney transplantation.
  • To compare transplant outcomes between ECMO donors (VA-ECMO and VV-ECMO) and non-ECMO donors stratified by Kidney Donor Profile Index (KDPI).

Main Methods:

  • Retrospective review of organ procurement organization and transplant network databases.
  • Comparison of kidney transplants from VA-ECMO and VV-ECMO donors versus KDPI-stratified non-ECMO donors.
  • Multivariable regression analysis to assess ECMO support and donor factors predicting graft survival.

Main Results:

  • 128 kidney transplants from 78 ECMO donors (80 VA-ECMO, 48 VV-ECMO) were analyzed.
  • VA-ECMO donor kidneys showed similar delayed graft function and post-transplant renal function to KDPI-matched non-ECMO donors.
  • VA-ECMO kidneys had superior or similar graft survival compared to low-KDPI non-ECMO kidneys, while VV-ECMO kidneys had inferior survival except for the lowest KDPI group.
  • VV-ECMO, but not VA-ECMO, was associated with increased risk of graft loss (HR 2.18).
  • High KDPI, older donor age, higher BMI, hypertension, and diabetes were risk factors in ECMO donors.

Conclusions:

  • Kidney transplantation from carefully selected ECMO donors can safely increase the available donor pool.
  • VA-ECMO donors represent a viable option for kidney transplantation.
  • Further research is needed to establish optimal practices for utilizing kidneys from ECMO-supported donors, particularly VV-ECMO donors.