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Clinical characteristics of mechanically ventilated children in pediatric intensive care unit: A single-center study

Cansu Durak1, Kubra Boydag Guvenc1

  • 1Department of Pediatric Intensive Care, Health Sciences University, Sancaktepe Sehit Prof. Dr. Ilhan Varank Training and Research Hospital, Istanbul, Turkiye.

Northern Clinics of Istanbul
|October 13, 2023
PubMed

Insights

Mechanical ventilation (MV) is crucial in pediatric intensive care units (PICUs), but carries risks. Sepsis significantly increases mortality in children requiring MV, highlighting the need for experienced PICU teams.

Area of Science:

  • Pediatric Critical Care Medicine
  • Respiratory Support
  • Mechanical Ventilation

Background:

  • Mechanical ventilation (MV) is a life-saving intervention for critically ill children.
  • It supports cardiovascular and respiratory systems during severe illness.
  • Challenges in pediatric intensive care units (PICUs) include optimizing MV and managing associated risks.

Purpose of the Study:

  • To assess the demographic characteristics, clinical features, indications, complications, and outcomes of pediatric patients receiving MV.
  • To analyze the impact of different conditions on MV requirements and patient prognosis in a tertiary hospital PICU in a developing country.

Main Methods:

  • Retrospective review of pediatric patients (0-18 years) who underwent MV.
  • Data collected from February 2022 to January 2023 at a specific tertiary hospital PICU.
  • Analysis included demographic profile, clinical data, MV indications, complications, and patient outcomes.

Main Results:

  • 139 patients were analyzed; 56.8% were male, with a median age of 36 months.
  • Respiratory diseases were the most common indication for MV (38.8%).
  • A 19.4% mortality rate was observed, significantly associated with sepsis (p=0.001), which also required prolonged respiratory support.

Conclusions:

  • Mechanical ventilation is indispensable in PICUs but associated with morbidity and mortality.
  • Sepsis is a significant risk factor for mortality in pediatric patients on MV.
  • Experienced PICU teams are vital for improving patient prognosis and outcomes.
Abstract

Keywords:
Critical carecritical illnessmechanical ventilationmortality

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