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Related Concept Videos

Development of the Limb Synovial Joints01:07

Development of the Limb Synovial Joints

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Joints form during embryonic development in conjunction with the formation and growth of the associated bones. The embryonic tissue that gives rise to all bones, cartilage, and connective tissues of the body is called mesenchyme.
The mesenchymal stem cells differentiate into chondrocytes that form the hyaline cartilage, and later the cartilaginous model of the bone. This model further transforms into a bone. This process is known as endochondral ossification.
During development, the limbs...
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Structural Joints: Synovial Joints01:16

Structural Joints: Synovial Joints

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Synovial joints are the most common type of joint in the body. A key structural characteristic for a synovial joint is the presence of a joint cavity. This fluid-filled space is where the articulating surfaces of the bones contact each other. Also, unlike fibrous or cartilaginous joints, the articulating bone surfaces at a synovial joint are not directly connected to each other with fibrous connective tissue or cartilage. This gives the bones of a synovial joint the ability to move smoothly...
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Structural Joints: Cartilaginous Joints01:17

Structural Joints: Cartilaginous Joints

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As the name indicates, at a cartilaginous joint, the adjacent bones are united by cartilage, a tough but flexible type of connective tissue. Unlike synovial joints, these types of joints lack a joint cavity and involve bones joined together by either hyaline cartilage or fibrocartilage.
There are two types of cartilaginous joints:
Synchondrosis
A synchondrosis ("joined by cartilage") is a cartilaginous joint where bones are connected by hyaline cartilage. Synchondrosis may be temporary...
2.3K
Growth of Cartilage and Bone Tissue01:27

Growth of Cartilage and Bone Tissue

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Chondrocytes form a temporary cartilaginous model by dividing and secreting a thick gel-like extracellular matrix. Once the chondrocytes undergo programmed cell death, osteoblasts enter the site of the cartilaginous model. The process of replacing the temporary cartilaginous model with bone in an ordered manner is called endochondral ossification. In endochondral ossification, not all of the cartilage is replaced by bone tissue. Some cartilage that performs a protective and supportive function...
3.4K
Bone Formation by Endochondral Ossification01:24

Bone Formation by Endochondral Ossification

4.5K
Bone formation, or ossification, begins around the sixth to seventh week of embryonic development. Most bones develop from a cartilaginous template through the process of endochondral ossification. Cartilage formation begins when clusters of mesenchymal cells differentiate into chondrocytes. These chondrocytes proliferate rapidly and secrete an extracellular matrix that becomes encased in a membrane called the perichondrium. The resulting cartilage model provides a template that resembles the...
4.5K
Knee Joint01:23

Knee Joint

1.9K
The knee joint is the most complicated joint in the body. It consists of three articulations– two tibiofemoral and one patellofemoral. As is characteristic of synovial joints, the knee joint has a thin articular capsule that partially surrounds this joint cavity. Additionally, several ligaments, muscles, and cartilaginous structures support the movement of the knee.
A total of seven ligaments support the knee joint. The patellar ligament, which is also attached to the quadriceps femoris...
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Revue medicale de Liege·2023
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Related Experiment Video

Updated: Jul 13, 2025

A 3D System for Culturing Human Articular Chondrocytes in Synovial Fluid
09:58

A 3D System for Culturing Human Articular Chondrocytes in Synovial Fluid

Published on: January 31, 2012

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[Synovial chondromatosis].

Arnaud Janssen1, Geoffroy Odekerken2

  • 1Service de Médecine physique, CHU Liège, Belgique.

Revue Medicale De Liege
|October 13, 2023
PubMed
Summary

Synovial chondromatosis is a rare joint pathology causing cartilaginous bodies to form from the synovial membrane. Treatment involves removing these loose bodies, often with synovectomy, to restore joint function.

Area of Science:

  • Orthopedics
  • Rheumatology
  • Pathology

Background:

  • Synovial chondromatosis is a rare condition characterized by the development of cartilaginous bodies within the synovial membrane.
  • It most commonly affects weight-bearing joints, leading to significant joint dysfunction.

Observation:

  • The condition presents with joint swelling and restricted mobility.
  • Primary and secondary forms of synovial chondromatosis are recognized.

Findings:

  • Cartilaginous loose bodies develop from the synovial membrane and can migrate within the joint.
  • Cross-sectional imaging is the preferred diagnostic modality.

Implications:

  • Surgical removal of cartilaginous loose bodies, potentially combined with synovectomy, is the primary treatment.
Keywords:
KneeSynovial chondromatosis

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  • Effective management aims to alleviate symptoms and improve joint function.