Related Experiment Video

Updated: Jul 13, 2025

Production of a SARS-CoV-2 Virus-Like-Particle System to Investigate Viral Life Cycles In Vitro
09:26

Production of a SARS-CoV-2 Virus-Like-Particle System to Investigate Viral Life Cycles In Vitro

Published on: June 6, 2025

225

Distinct motifs in the E protein are required for SARS-CoV-2 virus particle formation and lysosomal deacidification

Koya Miura1, Youichi Suzuki2, Kotaro Ishida1

  • 1Department of Biochemistry and Molecular Biology, Faculty of Agriculture and Life Science, Hirosaki University , Aomori, Japan.

Journal of Virology
|October 13, 2023
PubMed
Abstract

Keywords:
ESCRT pathwayHiBiT tagPDZ domain proteinPDZ-binding motifenvelope (E) proteinlysosomal pHpH indicatorsevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)virion secretionvirus-like particle (VLP)

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